This study investigated the influence of CFRP composite wrapping techniques on the load–deflection and strain relationships of non-prismatic RC beams. A total of twelve non-prismatic beams with and without openings were tested in the present study. The length of the non-prismatic section was also varied to assess the effect on the behavior and load capacity of non-prismatic beams. The strengthening of beams was performed by using carbon fiber-reinforced polymer (CFRP) composites in the form of individual strips or full wraps. The linear variable differential transducers and strain gauges were installed at the steel bars to observe the load–deflection and strain responses of non-prismatic RC beams, respectively. The cracking behavior of unstrengthened beams was accompanied by excessive flexural and shear cracks. The influence of CFRP strips and full wraps was primarily observed in solid section beams without shear cracks, resulting in enhanced performance. In contrast, hollow section strengthened beams exhibited minor shear cracks alongside the primary flexural cracks within the constant moment region. The absence of shear cracks was reflected in the load–deflection curves of strengthened beams, which demonstrated a ductile behavior. The strengthened beams demonstrated 40% to 70% higher peak loads than control beams, whereas the ultimate deflection was increased up to 524.87% compared to that of the control beams. The improvement in the peak load was more prominent as the length of the non-prismatic section increased. A better improvement in ductility was achieved for the case of CFRP strips in the case of short non-prismatic lengths, whereas the efficiency of CFRP strips was reduced as the length of the non-prismatic section increased. Moreover, the load–strain capacity of CFRP-strengthened non-prismatic RC beams was higher than the control beams.