To solve the issues of the open-loop control accuracy in a proton exchange membrane (PEM) fuel cell power conditioning system (PCS) with active clamp push-pull DC/DC converter for input current ripple reduction, a novel closed-loop digital-controlled method is proposed. The proposed PEM fuel cell PCS consists of a high-efficiency highstep-up current-fed resonant push-pull DC/DC converter and a half-bridge inverter. A fully digital-controlled strategy in the active-clamped circuit is employed to reduce the voltage spike and low frequency current ripple (LFCR) on the power switches for improving the lifespan of PEM fuel cell and raising the system reliability. By using the closed-loop current ripple reduction control, the LFCR is further reduced. A 300 W prototype is implemented and tested. Experimental results show that the minimum efficiency at full load is about 94.8% and the ripple current is less than 1.2% of the rated input current.