Effect of low dietary levels of glucose, fructose and sucrose on rat lipid metabolism

Mukherjee, Sourav; Basu, Mitali; Trivedi, Kamaxi H.

doi:10.1016/s0368-1319(69)80014-1

Cited by 15 publications

(3 citation statements)

References 30 publications

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“…Differ ences between strains in their response to dietary carbohydrates have been previously reported (5). Therefore, the bigger response to low levels of dietary sucrose and fructose demonstrated by Mukherjee et al (19) might perhaps be attributed to a strain more sensitive than that used in the present study. This may also account for the differences observed between the present results and those of Bruckdorfer et al (9).…”

Section: Discussionmentioning

confidence: 44%

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Effect of Dietary Sucrose and Fructose on the Metabolism and Lipid Fractions in Liver in the Rat

Tuovinen

Bender²

1975

Ann Nutr Metab

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Male and female weanling rats were fed one of the following diets for 26 weeks: 60 % (w/w) starch as control (59 % of energy content); 20 (20), 40 (39) or 60 % (59 %) sucrose; or 20 % (20 %) fructose. With increasing levels of dietary sucrose the livers of male rats but not those of females, were progressively heavier. Livers of rats of both sexes showed progressively higher total lipid levels mainly as a result of high triglyceride levels. The 20 % fructose diet produced the same effect as the 40 % sucrose diet. The incorporation of ¹⁴C-glucose into liver lipids in vitro, and the production of ¹⁴CO₂ were both depressed by sucrose and fructose feeding in both sexes.

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Section: Discussionmentioning

confidence: 44%

“…Mukher jee et al (19), using 12 % sucrose and fructose diets, also demonstrated a signifi cant increase in liver triglycerides of rats in 30 days. Literature on the influence of dietary carbohydrates on cholesterol levels indicates extensive conflicts be tween various studies (1,13,15).…”

Section: Discussionmentioning

confidence: 90%

Effect of Dietary Sucrose and Fructose on the Metabolism and Lipid Fractions in Liver in the Rat

Tuovinen

Bender²

1975

Ann Nutr Metab

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“…It is not quite clear, however, which components of our diet can be held responsible. There is an increasing amount of evidence regarding different effects of various carbohydrates on lipid metabolism [1,2 13-15, 19], in particular of sucrose and fructose on plasma triglycerides [10,18,20,21]. The mechanism for the production of hypertriglyceridemia, however, has not yet been satisfactorily explained.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Starch, Sucrose, Glucose and Fructose on Lipid Metabolism in Rats

Laube

Fußgänger

et al. 1973

Ann Nutr Metab

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This study records slower weight gain, greater body and liver fat, higher serum triglycerides and free fatty acids in rats fed a high sucrose diet or a mixture of an equivalent amount of glucose and fructose given as monosaccharides, in comparison to rats on high starch diets. There was no significant difference, however, between rats fed the sucrose-rich diet compared to the glucose/fructose diet. There seems to be good evidence that there is no specific effect of sucrose on lipid metabolism. Rather hypertriglyceridemia is due to the fructose and increased lipogenesis due to the glucose moietyof the sucrose molecule.

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Diet and Human Atherosclerosis — Carbohydrates

Macdonald

1975

Diet and Atherosclerosis

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Effect of low dietary levels of glucose, fructose and sucrose on rat lipid metabolism

Cited by 15 publications

References 30 publications

Effect of Dietary Sucrose and Fructose on the Metabolism and Lipid Fractions in Liver in the Rat

Effect of Dietary Sucrose and Fructose on the Metabolism and Lipid Fractions in Liver in the Rat

The Effect of Starch, Sucrose, Glucose and Fructose on Lipid Metabolism in Rats

Diet and Human Atherosclerosis — Carbohydrates

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