Effect of low-dose intravenous ketamine on postoperative pain following cesarean section under spinal anesthesia: A prospective cohort study, Ethiopia

Samuel, Hirbo; Aweke, Senait; Tuni, Jemal

doi:10.1016/j.amsu.2022.103570

Cited by 5 publications

(3 citation statements)

References 30 publications

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“…With the continuous advancements in technology, caesarean section has become the preferred method of delivery for women who are unable to have a natural birth 34 . However, caesarean section is an unnatural method of delivery that requires an open abdomen and anaesthesia, and is prone to serious complications, including urinary retention, incision infection, abdominal distension and post‐partum haemorrhage, delaying the recovery of the body's functions and worsening prognosis 5,35,36 . Several factors can contribute to high requirements for clinical nursing work, and clinics need to strengthen the nursing care of caesarean section mothers to provide effective nursing interventions.…”

Section: Discussionmentioning

confidence: 99%

“… 34 However, caesarean section is an unnatural method of delivery that requires an open abdomen and anaesthesia, and is prone to serious complications, including urinary retention, incision infection, abdominal distension and post‐partum haemorrhage, delaying the recovery of the body's functions and worsening prognosis. 5 , 35 , 36 Several factors can contribute to high requirements for clinical nursing work, and clinics need to strengthen the nursing care of caesarean section mothers to provide effective nursing interventions. Although conventional nursing provides basic nursing measures, it fails to meet the humanistic care needs of mothers and cannot alleviate adverse emotions; therefore, the quality of postnatal care cannot be effectively improved.…”

Section: Discussionmentioning

confidence: 99%

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Effect of humanised care on the surgical site wound infection after caesarean: A meta‐analysis

Wang,

Tian

et al. 2023

International Wound Journal

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Herein, a meta‐analysis was conducted to systematically evaluate the effect of humanised care on maternal postoperative wound infections in patients who underwent caesarean section. A computerised search of Embase, Cochrane Library, PubMed, Web of Science, China National Knowledge Infrastructure, Chinese Biomedical Literature Database and Wanfang database was performed, supplemented by a manual search from database inception to September 2023, to collate randomised controlled trials (RCTs) regarding the application of humanised care during the perioperative period of caesarean section. Two researchers screened and selected studies identified according to inclusion and exclusion criteria, and the included literature was evaluated for quality, extracted information and required data. Data analysis was performed using RevMan 5.4 software. Twenty RCTs comprising 2408 patients were included. The results revealed the humanised care group had a lower incidence of postoperative wound infections (0.83% vs. 4.32%, odds ratio [OR]: 0.26, 95% confidence interval [CI]: 0.15–0.46, p < 0.00001) and fewer postoperative complications than the conventional care group (4.32% vs. 16.35%, OR: 0.23, 95% CI: 0.16–0.31, p < 0.00001), with lower anxiety scores (standardised mean difference [SMD]: −3.15, 95% CI: −3.90 to −2.40, p < 0.00001) and depression scores (SMD: −3.68, 95% CI: −4.49 to −2.88, p < 0.00001). The application of humanised care during the perioperative period of caesarean section can prevent postoperative wound infection, reduce postoperative complications and help alleviate maternal anxiety and depression, which is worthy of clinical promotion and application.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effect of humanised care on the surgical site wound infection after caesarean: A meta‐analysis

Wang,

Tian

et al. 2023

International Wound Journal

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“…Numerous studies have demonstrated that using ketamine immediately following surgery can delay the time when initial postoperative analgesia is requested and can decrease the use of morphine, tramadol, and other opioids. [106][107][108] In addition, the price of ketamine is significantly lower in Africa, where a 500-mg vial of ketamine costs $4 in Rwanda, compared to $40 in Canada. Lastly, severe hemodynamic disorders rarely occur with ketamine, and as a result, ketamine might be considered for managing postoperative discomfort.…”

Section: Medicine Shortage and Restrictionmentioning

confidence: 99%

Review of the Current Situation of Postoperative Pain and Causes of Inadequate Pain Management in Africa

Gao¹,

Mu²,

Lin³

et al. 2023

JPR

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Postoperative pain is one of the most prevalent complications following surgery, and more than 47% of surgical patients endure postoperative discomfort worldwide. In Africa, due to resource shortages and other issues, postoperative pain is substantially more common when compared to developed countries. Severe postoperative pain has many negative effects, including possibly death, which can burden both individuals and society as a whole. Therefore, effectively controlling postoperative pain is becoming increasingly important. To enhance the effectiveness of future pain management, a thorough analysis of the current reasons for inadequate postoperative pain management is necessary. In this article, the present situations of occurring postoperative pain, children's postoperative pain, and pain management in Africa are reviewed, based on relevant and recent literature. In particular, the reasons for inadequate postoperative pain management in Africa are detailed in this article from five perspectives: the inadequate assessment of postoperative pain, the knowledge gap among medical professionals, the patients' misconceptions, the scarcity of resources, and the lack of medications. Additionally, we offer appropriate solutions following various factors.

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Simultaneous quantitation of ketamine, norketamine and dehydronorketamine in human milk using a novel ultra high-performance liquid chromatography-mass spectrometry (UPLC-MS/MS) assay

Shahane

Zhao

Pakalapati

et al. 2023

Journal of Pharmaceutical and Biomedical Analysis

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Effect of low-dose intravenous ketamine on postoperative pain following cesarean section under spinal anesthesia: A prospective cohort study, Ethiopia

Cited by 5 publications

References 30 publications

Effect of humanised care on the surgical site wound infection after caesarean: A meta‐analysis

Effect of humanised care on the surgical site wound infection after caesarean: A meta‐analysis

Review of the Current Situation of Postoperative Pain and Causes of Inadequate Pain Management in Africa

Simultaneous quantitation of ketamine, norketamine and dehydronorketamine in human milk using a novel ultra high-performance liquid chromatography-mass spectrometry (UPLC-MS/MS) assay

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