Effect of Low-Intensity vs High-Intensity Home-Based Walking Exercise on Walk Distance in Patients With Peripheral Artery Disease

McDermott, Mary McGrae; Spring, Bonnie; Tian, Lu; Treat‐Jacobson, Diane; Ferrucci, Luigi; Lloyd‐Jones, Donald M.; Zhao, Lihui; Polonsky, Tamar S.; Kibbe, Melina R.; Bazzano, Lydia A.; Guralnik, Jack M.; Forman, Daniel E.; Rego, Al; Zhang, Dongxue; Domanchuk, Kathryn; Leeuwenburgh, Christiaan; Sufit, Robert; Smith, Brian K.; Manini, Todd M.; Criqui, Michael H.; Rejeski, W. Jack

doi:10.1001/jama.2021.2536

Cited by 133 publications

(201 citation statements)

References 39 publications

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“…A search of the literature identified a total of 8693 studies, of which 27 were included in the full review following screening (online supplementary material). Twelve of the included studies were randomised controlled trials, [22][23][24][25][26][27][28][29][30][31][32][33] and the remaining 15 were nonrandomised. [34][35][36][37][38][39][40][41][42][43][44][45][46][47][48] The included studies comprised a total of 2351 participants, 1642 of whom received a home-based intervention, representing a total of 147,810 patient-hours.…”

Section: Study Selectionmentioning

confidence: 99%

Safety of home-based exercise for people with intermittent claudication: A systematic review

et al. 2021

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Intermittent claudication (IC) is a classic symptom of peripheral artery disease, with first line treatment being supervised exercise therapy (SET). Despite this, SET is frequently underutilised, and adherence is often poor. An alternative option are home-based exercise programmes (HBEP). Although HBEPs are well tolerated, to the authors’ knowledge, no research has assessed their safety. The aim of this review was to assess the safety of HBEPs in people living with IC. We performed an electronic search of the MEDLINE, CINAHL, and Cochrane Library databases. The main parameter of interest was complication rate, calculated as the number of related adverse events per patient-hours. Subanalysis was undertaken to determine differences in safety for studies that did and did not include pre-exercise cardiac screening, and for studies with exercise at low, moderate, and high levels of claudication pain. Our search strategy identified 8693 results, of which 27 studies were included for full review. Studies included 1642 participants completing 147,810 patient-hours of home-based exercise. Four related adverse events were reported, three of which were cardiac in origin, giving an all-cause complication rate of one event per 36,953 patient-hours. Three of these events occurred following exercise to high levels of claudication pain, and one occurred with pain-free exercise. All four events occurred in studies without cardiac screening. Based on the low number of related adverse events, HBEPs appear to be a safe method of exercise prescription for people with IC. Our results strengthen the rationale for providing alternative exercise options for this population. PROSPERO Registration No.: CRD42021254581

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Section: Study Selectionmentioning

confidence: 99%

Safety of home-based exercise for people with intermittent claudication: A systematic review

et al. 2021

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“…Many authors suggest that effective home-based exercise programs for individuals suffering from diabetes complicated with PAD may require ongoing contact with a physiotherapist, at least during the first six months [ 24 , 47 , 56 , 64 ], to consolidate good habits in patients and to confirm how to perform marching exercises well. A study published in April 2021 by McDermott et al identified the need for home-based exercise in patients with PAD and demonstrated the higher effectiveness of high intensity of these exercises [ 65 ]. The effectiveness of home exercise therapy was also confirmed in a study by Fukaya et al [ 66 ].…”

Section: Kinesitherapymentioning

confidence: 99%

Patients with Diabetes Complicated by Peripheral Artery Disease: the Current State of Knowledge on Physiotherapy Interventions

Hap

Biernat

Konieczny

2021

Journal of Diabetes Research

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Diabetes mellitus (DM) is one of the major public health problems that account for morbidity, mortality, and disability worldwide. The presence of DM increases the risk of peripheral artery disease (PAD), as well as accelerates its course, making these patients more susceptible to ischemic events and impaired functional status. Unfortunately, alternative treatments for vascular complications in diabetes are poorly researched. Physiotherapy (kinesitherapy combined with different physical therapy agents) in individuals with DM and coexisting PAD may offer an important complementary therapy alternative. Early therapeutic measures can significantly improve patient outcomes, reduce cardiovascular risk, and improve daily life quality. The article provides an update on the current state of knowledge on physiotherapy interventions in the course of DM in patients with coexisting PAD.

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“…Ninety patients confirmed diagnoses with COVID-19 were consulted at Al-Kindy Teaching Hospital (Al-Shifa center) from October 2020 till April 2021. All patients in this study were from Baghdad, diagnosed according to the WHO procedure [10].…”

Section: Study Design and Participantsmentioning

confidence: 99%

Intestinal Parasitic Infections in Relation to COVID-19 in Baghdad City

AL-Khaliq

Mahdi

Nasser

2021

Open Access Maced J Med Sci

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BACKGROUND: COVID-19 is resulted from severe acute respiratory syndrome coronavirus 2, which initiated in China in December 2019. Parasites are efficient immune modulators because their ability to stimulate an immune response in infected persons. AIM: This study aims to detect if there is a probable relationship between intestinal parasitic infections and COVID-19. METHODS: Ninety patients consulted at Al-Kindy Teaching Hospital (Al-Shifa center) from October 2020 till April 2021, confirmed infection with COVID-19 by PCR. Stool examination was done for detecting intestinal parasites. RESULTS: From 90 patients, males were 63 (70%), with median age 32 years, while females were 27 (30%), with age 24–44 years. Asymptomatic patients were 8.1 (9%), patients with moderate symptoms 22.5 (25%) cases, while the rest were 59.4 (66%) cases who required enter to the intensive care unit, with symptoms including cough (80%), dyspnea (74%), fever (56%), headache (43%), chest pain (37%), sore throat (35%), myalgia (32%), diarrhea (27%), and hemoptysis (3%). CONCLUSION: There is inverse relationship between parasitic infection and COVID-19 infections, and it is significant to understand the action between parasites and microbiome, also its function in COVID-19 pathogenicity.

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Effect of Low-Intensity vs High-Intensity Home-Based Walking Exercise on Walk Distance in Patients With Peripheral Artery Disease

Cited by 133 publications

References 39 publications

Safety of home-based exercise for people with intermittent claudication: A systematic review

Safety of home-based exercise for people with intermittent claudication: A systematic review

Patients with Diabetes Complicated by Peripheral Artery Disease: the Current State of Knowledge on Physiotherapy Interventions

Intestinal Parasitic Infections in Relation to COVID-19 in Baghdad City

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