In this research work, we offer an epidemic model for monkeypox virus infection with the help of non-integer derivative as well as classical ones. The model takes into account every potential connection that can aid in the spread of infection among the people. We look into the model’s endemic equilibrium, disease-free equilibrium, and reproduction number [Formula: see text]. In addition to this, we concentrated on the qualitative analysis and dynamic behavior of the monkeypox virus. Through fixed point theorem, Banach’s and Schaefer’s are applied to study the existence and uniqueness of the solution of the suggested system of the monkeypox virus infection. We provide the necessary criteria for the recommended fractional system’s Ulam–Hyers stability. Furthermore, a numerical approach is used to study the solution routes and emphasize how the parameters affect the dynamics of the monkey pox virus. The most crucial features of the dynamics of the monkeypox virus are noticed and suggested to decision-makers.