Effect of Malnutrition at the Time of Diagnosis on the Survival of Children Treated for Cancer in El Salvador and Northern Brazil

Pedrosa, Francisco; Bonilla, Miguel; Liu, Aiyi; Smith, Karen; Davis, D. R.; Ribeiro, Raul C.; Wilimas, Judith A.

doi:10.1097/00043426-200011000-00005

Cited by 61 publications

(47 citation statements)

References 7 publications

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“…Nevertheless, other studies did not report similar associations 14 15. More importantly, two recent systematic reviews of 46 studies suggest that the evidence pertaining to malnourishment has largely been based on paediatric cancer patients in developed countries 16 17.…”

Section: Introductionmentioning

confidence: 99%

Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective

Conner

Avilés-Robles

Asdahl

et al. 2016

BMJ Support Palliat Care

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Section: Introductionmentioning

confidence: 99%

Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective

Conner

Avilés-Robles

Asdahl

et al. 2016

BMJ Support Palliat Care

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“…The intuitive relationship between poor nutritional status and a poor prospect for survival in children with cancer has been confirmed in most studies, but not in all 1, 9. Altered pharmacokinetics, more severe toxicity (neutropenia) and delay of chemotherapy have been reported in children with malnutrition 10.…”

Section: Introductionmentioning

confidence: 99%

Nutritional status at admission of children with cancer in Malawi

Israëls

Chirambo

Caron

et al. 2008

Pediatric Blood & Cancer

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“…4 When we compared our rate of malnutrition with other studies involving Brazilian children with malignant neoplasms, we observed that our rate was lower than the others, 15,17 which is a fact that warrants more profound analysis, since both studies used similar methodology to ours to define malnutrition.…”

Section: Discussionmentioning

confidence: 60%

Linfoma não-Hodgkin na infância: características clínico-epidemiológicas e avaliação de sobrevida em um único centro no Nordeste do Brasil

Pedrosa¹,

Pedrosa²,

Lins³

et al. 2007

J. Pediatr. (Rio J.)

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Objective: To describe the clinical and demographic characteristics of non-Hodgkin's lymphoma patients diagnosed at the Pediatric Oncology Unit at the Instituto Materno-Infantil Professor Fernando Figueira (IMIP) over a 9-year period, and also to describe their survival rates and possible associations between the survival rates and the clinical and demographic characteristics analyzed in the study.Methods: This was a cross-sectional study. Data were collected by a retrospective review of the charts of all 110 patients admitted to our unit during the period of May 1994 through May 2003. Probability of survival was calculated in accordance with the techniques of Kaplan-Meier, using log rank to evaluate differences between the groups. Results:The average age was 6.1 years. The male/female ratio was 2.4:1. The most frequent histological subtype was Burkitt's lymphoma. The majority of patients had been diagnosed with advanced disease (stage III or IV of Murphy's Classification) and was from rural areas. Family income per capita was lower than 1/2 minimum wage in 36.4% of cases; maternal illiteracy was observed in 12.7% of cases. The 5-year overall survival and disease-free survival rates were 70±4% and 68.4±4%, respectively. None of the clinical-demographic characteristics had a significant association with the probability of survival (p > 0.05). Conclusion:Children admitted to the IMIP seemed to be affected by non-Hodgkin lymphoma at a younger age, with a higher incidence of Burkitt's lymphoma and with survival rates similar to those described in the literature of developed countries. No clinical demographic characteristics had a statistically significant association with prognosis.

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Effect of Malnutrition at the Time of Diagnosis on the Survival of Children Treated for Cancer in El Salvador and Northern Brazil

Abstract: We found no relationship between nutritional status and survival in these patients. This implies that future protocols for use in developing countries can be designed to provide optimal treatment intensity despite the high incidence of malnutrition.

Cited by 61 publications

References 7 publications

Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective

Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective

Nutritional status at admission of children with cancer in Malawi

Linfoma não-Hodgkin na infância: características clínico-epidemiológicas e avaliação de sobrevida em um único centro no Nordeste do Brasil

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