Effect of malnutrition on postoperative results after pancreatic resection: An entropy balancing analysis

Ricci, Claudio; Serbassi, Francesco; Ingaldi, Carlo; Alberici, Laura; Grego, Davide G.; Daniela, Di Mauro; Raffele, Emilio De; Vicennati, Valentina; Pironi, Loris; Sasdelli, Anna Simona; Casadei, Riccardo

doi:10.1016/j.clnu.2022.06.031

Cited by 4 publications

(2 citation statements)

References 30 publications

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“…31 Two recent metaanalyses concluded that immunonutrition reduced infectious complications and length of stay after a PD. 32,33 The PANasta trial represents the most robust analysis comparing two different techniques of pancreato-jejunal anastomosis and reported no difference between the Blumgart and Cattel-Warren techniques. 34 Ellis et al have recently published the results of a robust RCT demonstrating a significant reduction in rates of CR-POPF and surgical site infections by implementing piperacillin-tazobactam in perioperative antibiotic prophylaxis for patients undergoing a PD.…”

Section: Risk Mitigation Strategies In Pdmentioning

confidence: 99%

Big data and RCT's in surgical oncology: Impact on improving hepatopancreatobiliary cancer surgical care on the global stage

Shrikhande,

Kunte,

Chopde

et al. 2023

Journal of Surgical Oncology

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Randomized controlled clinical trials (RCTs) are at the heart of “evidence‐based” medicine. Conducting well‐designed RCTs for surgical procedures is often challenged by inadequate recruitment accrual, blinding, or standardization of the surgical procedure, as well as lack of funding and evolution of the treatment strategy during the many years over which such trials are conducted. In addition, most clinical trials are performed in academic high‐volume centers with highly selected patients, which may not necessarily reflect a “real‐world” practice setting. Large databases provide easy and inexpensive access to data on a large and diverse patient population at a variety of treatment centers. Furthermore, large database studies provide the opportunity to answer questions that would be impossible or very arduous to answer using RCTs, including questions regarding health policy efficacy, trends in surgical practice, access to health care, the impact of hospital volume, and adherence to practice guidelines, as well as research questions regarding rare disease, infrequent surgical outcomes, and specific subpopulations. Prospective data registries may also allow for quality benchmarking and auditing. There are several high‐quality RCTs providing evidence to support current practices in hepatopancreatobiliary (HPB) oncology. Evidence from big data bridges the gap in several instances where RCTs are lacking. In this article, we review the evidence from RCTs and big data in HPB oncology identify the existing lacunae, and discuss the future directions of research in HPB oncology.

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Section: Risk Mitigation Strategies In Pdmentioning

confidence: 99%

Big data and RCT's in surgical oncology: Impact on improving hepatopancreatobiliary cancer surgical care on the global stage

Shrikhande,

Kunte,

Chopde

et al. 2023

Journal of Surgical Oncology

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show abstract

“…Studies have shown that ALB is an important indicator that affects the inflammatory reaction and nutritional status of patients, and low ALB indicates impaired immune function. 2,3 Some studies have shown that ALB is an important indicator that affects the inflammatory reaction and nutritional status of patients.…”

Section: An Assessment Of Perioperative Outcomes For Open Laparoscopi...mentioning

confidence: 99%

An assessment of perioperative outcomes for open, laparoscopic, and robot‐assisted pancreaticoduodenectomy

Yang¹,

Zhu

2022

Journal of Surgical Oncology

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Evaluation of five nutritional scores as predictors of postoperative outcome following pancreatic resection: A prospective, single-center study

Paiella,

Secchettin,

Azzolina

et al. 2024

Clinical Nutrition ESPEN

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Effect of malnutrition on postoperative results after pancreatic resection: An entropy balancing analysis

Cited by 4 publications

References 30 publications

Big data and RCT's in surgical oncology: Impact on improving hepatopancreatobiliary cancer surgical care on the global stage

Big data and RCT's in surgical oncology: Impact on improving hepatopancreatobiliary cancer surgical care on the global stage

An assessment of perioperative outcomes for open, laparoscopic, and robot‐assisted pancreaticoduodenectomy

Evaluation of five nutritional scores as predictors of postoperative outcome following pancreatic resection: A prospective, single-center study

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