Effect of mandibular nerve block on postoperative analgesia in patients undergoing oropharyngeal carcinoma surgery under general anaesthesia

Plantevin, Frédéric; Pascal, Jean; Morel, J.; Roussier, Marc; Charier, David; Prades, Jean-Michel; Auboyer, C.; Molliex, Serge

doi:10.1093/bja/aem242

Cited by 31 publications

(32 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Singhal et al [44] demonstrated that epidural Morphine provided better analgesia than IV Morphine with P < 0.05. Plantevin et al [41] investigated the effect of MNB on post-surgical pain, concluding that it was effective in reducing initial postoperative pain 24 hours after surgery. The trial comparing Piroxicam and Acetylsalicylic acid (ASA) conducted by Saxena et al.…”

Section: Resultsmentioning

confidence: 99%

“…However, there was no significant statistical change in VAS score at baseline or 28 days. Jovic et al [41] reported that Ketoprofen was superior to Metamizole in controlling post-surgical pain, however this was only statistically significant on day three of treatment (P < 0.05). Cervical epidural Morphine was shown to provide longer lasting analgesia compared to thoracic epidural by Georgiou et al [39] while also requiring smaller doses.…”

Section: Resultsmentioning

confidence: 99%

“…More complex pain management therapies can be employed such as nerve blocks as demonstrated by the study by Plantevin et al [41]. The study investigated the efficacy of using Ropivacaine, a local anaesthetic, to block the mandibular nerve.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Pharmacological and Other Interventions for Head and Neck Cancer Pain: a Systematic Review

Trotter¹,

Norton²,

Munn³

et al. 2012

JOMR

View full text Add to dashboard Cite

ObjectivesPain is a common complication in head and neck cancer. The aim of this paper is to evaluate the evidence from randomised control trials investigating pharmacological and non-pharmacological methods of pain management in head and neck cancer.Material and MethodsMedline, Embase and the Cochrane library databases were searched. Squamous cell carcinomas of the head and neck excluding nasopharyngeal and salivary gland cancers were included. The limits were "human" and "randomised clinical trials". A quality assessment was carried out.Results13 studies were included with a total of 644 participants. The primary outcome for most of these papers was pain control post-treatment. Levels of bias varied between the studies. Majority (12 out of the 13 studies) reported intervention to be superior to the control or standard therapy in pain management. Only 46% of the studies were carried out on an intention to treat basis. Two studies reported high dropout rates, with one at 66%.ConclusionsThere is insufficient evidence from randomised clinical trials to suggest an optimal pharmacological intervention for head and neck cancer pain post-treatment. Further high quality randomised clinical trials should be conducted to develop an optimal management strategy for head and neck cancer pain.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Pharmacological and Other Interventions for Head and Neck Cancer Pain: a Systematic Review

Trotter¹,

Norton²,

Munn³

et al. 2012

JOMR

View full text Add to dashboard Cite

show abstract

“…The local nerve block seemed to improve pain control under anesthesia in combination with lidocaine/fentanyl CRI. Local nerve blocks are commonly used in human medicine for surgical procedures on the mandible and maxilla and they have been shown to improve postoperative pain management [6, 24, 25, 31–33]. The increasing use of swine models for oral and maxillofacial surgical research justifies further investigation into the effectiveness of local nerve blocks.…”

Section: Discussionmentioning

confidence: 99%

Bupivacaine Mandibular Nerve Block Affects Intraoperative Blood Pressure and Heart Rate in a Yucatan Miniature Swine Mandibular Condylectomy Model: A Pilot Study

Bova

Cunha

Stout

et al. 2014

Journal of Investigative Surgery

View full text Add to dashboard Cite

Purpose/Aim The primary objective was to evaluate the effect of a bupivacaine mandibular nerve block on intraoperative blood pressure (BP) and heart rate (HR) in response to surgical stimulation and the need for systemic analgesics postoperatively. We hypothesized that a mandibular nerve block would decrease the need for systemic analgesics both intraoperatively and postoperatively. Materials and Methods Fourteen adult male Yucatan pigs were purchased. Pigs were chemically restrained with ketamine, midazolam, and dexmedetomidine and anesthesia was maintained with isoflurane inhalant anesthesia. Pigs were randomized to receive a mandibular block with either bupivacaine (bupivacaine group) or saline (control group). A nerve stimulator was used for administration of the block with observation of masseter muscle twitch to indicate the injection site. Invasive BP and HR were measured with the aid of an arterial catheter in eight pigs. A rescue analgesic protocol consisting of fentanyl and lidocaine was administered if HR or BP values increased 20% from baseline. Postoperative pain was quantified with a customized ethogram. HR and BP were evaluated at base line, pre-rescue, 10 and 20 min post-rescue. Results Pre-rescue mean BP was significantly increased (p = .001) for the bupivacaine group. Mean intraoperative HR was significantly lower (p = .044) in the bupivacaine versus saline group. All other parameters were not significant. Conclusion Addition of a mandibular nerve block to the anesthetic regimen in the miniature pig condylectomy model may improve variations in intraoperative BP and HR. This study establishes the foundation for future studies with larger animal numbers to confirm these preliminary findings.

show abstract

“…3,4 The use of mandibular nerve block has been demonstrated to decrease opioid consumption during general anesthesia and may provide superior analgesia as compared with systemic opioids. 5,6 Mandibular nerve block can be accomplished using either an extraoral or intraoral anatomical landmark approach. Traditionally, the intraoral technique, such as the inferior alveolar nerve block, has been reported to provide adequate anesthesia in approximately 80% to 85% of patients.…”

mentioning

confidence: 99%

A Novel Technique of Ultrasound-Guided Selective Mandibular Nerve Block With a Lateral Pterygoid Plate Approach

Kampitak

Tansatit

Shibata

2018

Regional Anesthesia and Pain Medicine

View full text Add to dashboard Cite

show abstract

Effect of mandibular nerve block on postoperative analgesia in patients undergoing oropharyngeal carcinoma surgery under general anaesthesia

Abstract: In this study, MNB performed before GA for oropharyngeal carcinoma surgery improved postoperative analgesia, resulting in reduced morphine consumption at 24 h and severe pain in fewer patients.

Cited by 31 publications

References 17 publications

Pharmacological and Other Interventions for Head and Neck Cancer Pain: a Systematic Review

Pharmacological and Other Interventions for Head and Neck Cancer Pain: a Systematic Review

Bupivacaine Mandibular Nerve Block Affects Intraoperative Blood Pressure and Heart Rate in a Yucatan Miniature Swine Mandibular Condylectomy Model: A Pilot Study

A Novel Technique of Ultrasound-Guided Selective Mandibular Nerve Block With a Lateral Pterygoid Plate Approach

Contact Info

Product

Resources

About