Effect of Maternal Body Mass Index on the Transcriptomic Network of Human First-Trimester Chorionic Villi

Editorial: Unravelling human placental (patho-) physiology at the epigenetic and transcriptome level

“…Thus, the bulk of placental tissue analyses, including bulk sequencing methods, simply profile an amalgamation of the individual signatures of constituent cell types, masking real cell resolution and compromising interpretation. This challenge has been the topic of various studies, with increasing interest and focusing on single cell RNA sequencing to identify the transcriptome and interactions of cells in the placenta (Wächter et al, 2022;Bao et al, 2023;Campbell et al, 2023;Dong et al, 2023;Garcia-Flores et al, 2023). This Research Topic also aimed to comprehensively address the heterogeneous composition of the placenta in healthy and pathological pregnancies.…”