Effect of medicaments used in endodontic regeneration technique on push-out bond strength of MTA and Biodentine

Abstract

The aim of the present study was to evaluate the effect of the intracanal medicaments used in regenerative endodontic treatment on push-out bond strength (PBS) of mineral trioxide aggregate (MTA) and Biodentine (BD). The root canals of 102 maxillary incisors were enlarged to simulate immature roots and were randomly divided into three groups (n D 34): a control group (no intracanal medicament) and two test groups, subjected to calcium hydroxide (CH) or triple antibiotic paste (TAP) medication for two weeks. After the medication removal, each group was divided in two subgroups and the coronal portion of each canal was filled with MTA or BD. After one week of storage, the coronal region of each root was horizontally sectioned and push-out test was performed. Data were analyzed by two-way analysis of variance and the Tukey post hoc test (P D 0.05). PBS values were significantly affected by the type of material (P < 0.001) and the type of medication used (P D 0.049), but no interaction was found (P D 0.97). The BD group showed significantly higher push-out resistance values than those of the MTA group (P < 0.001). TAP showed the lowest PBS values, which were significantly lower than those of the control group (P D 0.043) but not than those of CH (P D 0.229). After a two-week application period, TAP seemed to decrease the PBS of both cements, while CH did not. BD appeared to have higher PBS compared to MTA, regardless of medication.

Comparative analysis of bond strength to root dentin and compression of bioceramic cements used in regenerative endodontic procedures

“…The median resistance to displacement corresponded to 14.79 MPa, with a maximum value of 31.61 MPa and a minimum value of 2.97 MPa. This result is in accordance with those of several published studies, which presented values ranging from 2.16–56.7 MPa, thus highlighting the superior performance of Biodentine cement over other bioceramic formulations [ 24 33 34 35 ]. This performance can be explained by the biomineralization capability of this material.…”

Retention of BioAggregate and MTA as coronal plugs after intracanal medication for regenerative endodontic procedures: an ex vivo study

“…For BA, none of the ICMs differed from the control, and only CH showed better bond strength than DAP. However, variable results have been reported in the endodontic literature on the effects of the ICMs used in REPs on the retention of CSCs [ 17 18 19 20 ]. Our findings are in accordance with 1 study [ 20 ], partly in agreement with another [ 17 ], and in disagreement with others [ 18 19 ].…”

“…However, variable results have been reported in the endodontic literature on the effects of the ICMs used in REPs on the retention of CSCs [ 17 18 19 20 ]. Our findings are in accordance with 1 study [ 20 ], partly in agreement with another [ 17 ], and in disagreement with others [ 18 19 ]. Variations among studies may primarily be due to variations in experimental design, including the CSC types and durations of setting, as well as the ICM form, concentration, and method of removal [ 39 40 ] and the differential effects of ICMs on dentin, with which they were usually in contact for 3 weeks, as is the case for REPs.…”

“…All procedures were done under magnification (×13). All access cavities were sealed using a temporary filling (Cavit G, 3M ESPE) placed over a moistened cotton pellet in the pulp chamber [ 17 18 19 ] for 3 days. The specimens were stored at 37ºC and 100% relative humidity [ 17 18 19 20 ].…”

“…Some authors have investigated the effect of the ICM used in REPs on the bonding potential of MTA and Biodentine with varying results [ 17 18 19 20 ]. No studies to date have assessed the effect of such ICMs on the retention of BA; it was therefore of interest to conduct an ex vivo comparison of the retention of BA and MTA as coronal plugs after the prior application of different ICMs that are used in REPs.…”