Effect of Melissa officinalis capsule on the mental health of female adolescents with premenstrual syndrome: a clinical trial study

Abstract

Introduction In spite of its importance, the psychological health requirements of adolescents are ignored; due to the occurrence of mental disorders in this age group and also public interest in the use of supplementary and alternative treatments such as herbal drugs for mental disorders, this study was carried out aimed at examining the impact of the Melissa officinalis capsule on the psychological health of female adolescents. Methodology In this randomized clinical trial study, 100 female adolescents were assigned to two groups of either drug and placebo groups. The data collection tool includes demographic information recording note and General Health Standard Questionnaire (GHQ). Intervention has been done in the menstrual cycle during 3 successive months and patients received two 600 mg drug daily in the intervention group, and the control group received placebo. After the intervention, the scores of the participants' psychological health were measured in both groups and data were analyzed through independent t-test using SPSS software version 16. Results The study results showed that psychosomatic symptoms score (p < 0.001), anxiety and sleeping disorder (p < 0.001), and social function disorder (p = 0.021) in the experiment group was significantly less than that of the placebo group. Conclusion Based on the findings of this study, Melissa officinalis can decrease psychosomatic symptoms, sleeping disorder and anxiety, depression and disorder in social function in female adolescents.

The effect of aromatherapy on mental, physical symptoms, and social functions of females with premenstrual syndrome: A randomized clinical trial

“…Over the past decade, the use of complementary and alternative drugs has been increased to treat the problems of various groups of society, especially women, such as menopause, premenstrual syndrome, and sexual illness. [151617181920] The familiarity of the medical team and the research team has become even more prominent in this regard.…”

Melissa officinalis L. hydro‐alcoholic extract inhibits anxiety and depression through prevention of central oxidative stress and apoptosis

“…According to the literature, MO contains different classes of phytochemicals such as essential oils, terpenoids and polyphenolic compounds such as flavonoids, rosmarinic acid (RA) and tannins (Dastmalchi et al., 2008; De Sousa et al., 2004). In traditional medicine, MO has been extensively used for treatment of many psychological disorders such as nervous sleeping disorders, stress, anxiety and depression (Awad, Muhammad, Durst, Trudeau, & Arnason, 2009; Heydari, Dehghani, Emamghoreishi, & Akbarzadeh, 2018; Ibarra, Feuillere, Roller, Lesburgere, & Beracochea, 2010; Khodaei et al., 2017; Lin et al., 2015). It has anti‐inflammatory, anti‐microbial, anti‐oxidative, sedative and neuroprotective actions (López et al., 2009; Miraj, Rafieian, & Kiani, 2017).…”

Evaluation of aromatherapy with essential oils of Rosa damascena for the management of premenstrual syndrome

“…To the best of our knowledge, previous studies into of the effects of aromatherapy on the social functions of PMS have been limited, with some articles having reported that Melissa officinalis in capsule form was associated with reduced severity of physical, mental and social symptoms . It should be noted that ameliorating physical and mental symptoms of PMS could be expected to improve social functions.…”