Effect of metallic nanoparticles on exchange of chemical elements in broiler chickens

Gubajdullina, I. Z.; Gavrish, I. A.; Лебедев, С. В.

doi:10.1088/1755-1315/341/1/012169

Cited by 5 publications

(4 citation statements)

References 7 publications

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“…For this reason, researchers are increasingly interested in complexes of Cr with amino acids, such as methionine or glycine [ 18 , 19 ] as well as inorganic chromium nanoparticles [ 20 ]. It is believed that the lack of electric charge and the small size of chromium nanoparticles can modify their properties in a living organism and improve bioavailability relative to their standard counterparts [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

Assessment of DNA Methylation and Oxidative Changes in the Heart and Brain of Rats Receiving a High-Fat Diet Supplemented with Various Forms of Chromium

Dworzański

Cholewińska

Fotschki

et al. 2020

Animals

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The aim of the study was to determine how feeding rats a high-fat diet supplemented with various forms of chromium affects DNA methylation and oxidation reactions as well as the histology of heart and brain tissue. The rats received standard diet or high-fat diet and chromium at 0.3 mg/kg body weight (BW) in form of chromium (III) picolinate, chromium (III)-methionine, or nano-sized chromium. The content of malondialdehyde (MDA), protein carbonyl (PC), and 8-hydroxydeoxyguanosine (8-OHDG), the level of global DNA methylation and the activity of selected DNA repair enzymes were determined in the blood. In the brain and heart, the content of MDA, PC, 8-OHDG, and levels of global DNA methylation were determined. The brain was subjected to histological examination. The use of a high-fat diet was found to intensify epigenetic changes and oxidation reactions in the heart and brain. It was concluded that epigenetic changes and oxidation of lipids, proteins, and DNA in the heart and brain of rats resulting from the use of a high-fat diet cannot be limited by supplementing the diet with chromium. It was established that the use of chromium to supplement a high-fat diet intensifies the negative epigenetic and oxidative changes in the heart and brain, especially in the case of chromium nanoparticles.

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Section: Introductionmentioning

confidence: 99%

Assessment of DNA Methylation and Oxidative Changes in the Heart and Brain of Rats Receiving a High-Fat Diet Supplemented with Various Forms of Chromium

Dworzański

Cholewińska

Fotschki

et al. 2020

Animals

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“…In our study, the addition of Cr to the diet of chickens increased the concentration of Ca and Fe and decreased the concentration of Cu and Zn in their blood plasma. Similarly, Gubajdullina et al [41] found that supplementation of a chicken's diet with chromium (III) oxide nanoparticles at 50-400 µg/kg caused an increase in Fe and Ca content, while a decrease in Zn and Cu content in the body of birds. Iron is a cofactor for tyrosine hydroxylase and tryptophan hydroxylase, enzymes that are responsible for dopamine and serotonin synthesis, respectively [42], while magnesium affects norepinephrine level [43].…”

Section: Discussionmentioning

confidence: 92%

The Effect of Chromium Nanoparticles and Chromium Picolinate in the Diet of Chickens on Levels of Selected Hormones and Tissue Antioxidant Status

Stępniowska

Drażbo

Kozłowski

et al. 2019

Animals

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Simple Summary:We have postulated that supplementation with Cr can increase serotonin levels and improve the antioxidant status of chickens, with no adverse effect on the secretion of other hormones. Obtaining such results may be beneficial in high-density rearing of poultry exposed to many stressors. The studies compared the effects of two forms of Cr (Cr-Pic and Cr-NP) found at two doses 3 and 6 mg/kg. It was found that at the dose of 3 mg/kg, the expected beneficial results can be obtained (increase in serotonin and decrease in norepinephrine level), however, due to the deterioration of the antioxidative system, these studies should be continued to verify these results. Due to the adverse effect of Cr at 3 mg/kg on the antioxidant status of chickens, this level of Cr should not be considered in both forms Cr-Pic and Cr-NP as a feed additive for broiler chickens. In the future, studies on the potential beneficial effects of Cr on the organism should take into account doses lower than 3 mg/kg. Abstract:We have postulated that supplementation with Cr can increase serotonin levels and improve the antioxidant status of chickens, with no adverse effect on the secretion of other hormones. The study aimed to determine what form and dose of Cr more favorably affect the level of selected hormones (insulin, glucagon, serotonin, dopamine, noradrenaline, histamine, T3 and T4) and the antioxidant status (level of malondialdehyde and lipid peroxides, activity of superoxide dismutase and catalase) of chicken tissues. The experiment was carried out on chickens randomly divided into five treatment groups. The basal diets (control group) were supplemented with two levels of Cr (3 and 6 mg/kg) and two Cr sources: Cr-picolinate (Cr-Pic) and Cr-nano (Cr-NP) to obtain four experimental diets: 3 mg/kg Cr-Pic, 6.0 mg/kg Cr-Pic, 3.0 mg/kg Cr-NP. and 6.0 mg/kg Cr-NP. The addition of Cr in both forms increased the level of serotonin at a dose of 3 mg/kg and, at the same time, reduced the level of noradrenaline. The addition of Cr at 3 mg/kg, irrespective of the form used, regulated the level of hormones of carbohydrate metabolism (increasing insulin levels and reducing glucagon levels) and had an adverse effect on the antioxidant status of the liver and breast muscle. Due to the adverse effect of Cr at 3 mg/kg on the antioxidant status of chickens, this level of Cr should not be considered in both forms Cr-Pic and Cr-NP as a feed additive for broiler chickens. In the future, studies on the potential beneficial effects of Cr on the organism should take into account doses lower than 3 mg/kg. writing-original draft preparation, A.S.; Writing-Review and editing, K.O. and J.J.; Visualization, A.S.; Supervision, J.J.; Project administration, A.S., J.J. and K.O.; Funding acquisition, J.J. and K.O. All authors have read and agreed to the published version of the manuscript.

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“…A promising approach may be the use of nanoforms of microelements [7,8] which have unique properties that allow them to be competitive sources of chemical elements for mineral additives [9,10]. A number of studies confirmes the high efficiency of metal nanoforms compared to inorganic salts and other sources [11][12][13].…”

Section: The Effectiveness Of Various Forms Of Zn As Stimulators Of T...mentioning

confidence: 99%

ЭФФЕКТИВНОСТЬ РАЗЛИЧНЫХ ФОРМ ЦИНКА КАК ИММУНОМОДУЛЯТОРОВ В РАЦИОНАХ ЦЫПЛЯТ-БРОЙЛЕРОВ (Gallus gallus L.)

Сизова¹

2023

S-h. biol.

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Effect of metallic nanoparticles on exchange of chemical elements in broiler chickens

Cited by 5 publications

References 7 publications

Assessment of DNA Methylation and Oxidative Changes in the Heart and Brain of Rats Receiving a High-Fat Diet Supplemented with Various Forms of Chromium

Assessment of DNA Methylation and Oxidative Changes in the Heart and Brain of Rats Receiving a High-Fat Diet Supplemented with Various Forms of Chromium

The Effect of Chromium Nanoparticles and Chromium Picolinate in the Diet of Chickens on Levels of Selected Hormones and Tissue Antioxidant Status

ЭФФЕКТИВНОСТЬ РАЗЛИЧНЫХ ФОРМ ЦИНКА КАК ИММУНОМОДУЛЯТОРОВ В РАЦИОНАХ ЦЫПЛЯТ-БРОЙЛЕРОВ (Gallus gallus L.)

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