Effect of mindfulness yoga on anxiety and depression in early breast cancer patients received adjuvant chemotherapy: a randomized clinical trial

Abstract

Purpose The objective of this study is to explore the effects of a mindfulness yoga treatment on emotional disorders, fatigue, pain, and health-related quality of life in early-stage breast cancer patients. Methods The eligible 136 participants were randomly assigned 1:1 to the experimental group (mindfulness yoga + conventional care) and the control group (conventional care). The hospital anxiety and depression scale was used to assess anxiety and depression symptoms as the primary outcome. Secondary results comprised fatigue (RPFS-CV), pain (BPI-C), and health-related quality of life (FACT-B). Assessments were performed at baseline time, the 8th week, and the 20th week. Results The Experimental group had a better prognosis in comparison with those in the control group, especially for anxiety [inter-group effect, T1: 1.18 (95% CI 0.20–2.17; P = 0.018)], depression [T1: 1.49 (95% CI 0.48–2.50; P = 0.004)] and health-related life quality [T1: − 6.34 (95% CI − 11.81 to − 0.87; P = 0.023)]. While fatigue [T1: 0.23 (95% CI − 0.24–0.69; P = 0.337); T2: 0.27 (95% CI − 0.16–0.71; P = 0.219)] and pain [T1: 1.11 (95% CI − 0.05–2.27; P = 0.060); T2: 0.68 (95% CI − 0.27–1.62; P = 0.159)] were not different between the two groups. Conclusion In patients with early-stage breast cancer who had received adjuvant chemotherapy, treatment with mindfulness yoga is as effective as conventional care in improving physical function. Along with other treatments, mindfulness yoga may help alleviate anxiety and depression to improve the overall physical and mental health and quality of life of early-stage breast cancer patients. Chinese Clinical Trial Registry Registration number: ChiCTR2100052842, Reg. Date: 2021/11/6.

Effect of yoga on cancer-related fatigue in patients with breast cancer: A systematic review and meta-analysis

“…Finally, this study included 18 studies. [13–30] See the Flowchart . Table 1 shows the characteristics of the study and the participants.…”

“…The characteristics of the study and participants Author Liu [13] 2022 Cramer [17] 2015 Jong [22] 2018 Netherlands Yoga:47 Cai [26] 2022 China Yoga:36 CG:37 51.17 Li [28] Sensitivity analysis was conducted to identify the potential sources of heterogeneity. Even after excluding all studies, the findings remained unchanged, demonstrating that the findings were stable.…”

Comparative efficacy of mind‐body exercise for depression in breast cancer survivors: A systematic review and network meta‐analysis

“…Healthcare providers should include MBE as a routine supplementary treatment option alongside medication for patients suffering from mental health disorders. Notably, four included studies reported adverse events related to excessive or incorrect yoga practice (Danhauer et al, 2009; Jong et al, 2018; Kiecolt‐Glaser et al, 2014; Liu et al, 2022). Compared to Liuzijue or other types of qigong, Pilates and yoga are typically more challenging to perform and may need the assistance of a trained instructor to ensure proper execution (Shi et al, 2022).…”

Mindfulness-Based Therapy in Patients with Breast Cancer with Depression and Anxiety: A Literature Review

“…Depression and anxiety are the main psychological problems faced by breast cancer patients. Long-term psychological distress will reduce the survival rate of breast cancer patients, while firstline medications for emotional disorders will also increase the mortality of breast cancer patients (Liu et al, 2022). Therefore, mindfulness therapy as a non-pharmacological treatment is essential.…”

“…So far, studies on the impact of MBSR on breast cancer patients have not considered the effects according to the stage of breast cancer. Therefore, in a recent study, Liu et al (2022) conducted MBSR intervention on patients with early breast cancer. Early breast cancer patients are considered curable, but there is no denying that they will still have mental health problems and other complications.…”