Effect of Mir-21-3p on Intestinal Injury in Rats With Traumatic Hemorrhagic Shock Resuscitated With the Sodium Bicarbonate Ringer's Solution
Lei Li,
Hai Jiang,
Zhaolei Qiu
et al.
Abstract:Background
This study aims to determine the impact and mechanism of miR-21-3p on intestinal injury and intestinal glycocalyx during fluid resuscitation in traumatic hemorrhagic shock (THS), and the different impacts of sodium lactate Ringer's solution (LRS) and sodium bicarbonate Ringer's solution (BRS) for resuscitation on intestinal damage.
Methods
A rat model of THS was induced by hemorrhage from the left femur fracture. The pathological changes of i… Show more
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