2019
DOI: 10.1007/s00484-019-01748-4
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Effect of mud-bath therapy on the innate/inflammatory responses in elderly patients with osteoarthritis: a discussion of recent results and a pilot study on the role of the innate function of monocytes

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Cited by 21 publications
(10 citation statements)
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“…The main properties of peloids recognised are: their applications in thermotherapy [2,3,5,6] manifested by biological effects, metabolic and enzymatic activity, vascular, neuromuscular, analgesic and modifications of the viscoelastic properties of the tissues [7,8]; several other studies have confirmed their anti-inflammatory [9][10][11][12][13][14], chondroprotective [10,11] and immunological actions [10,[14][15][16] which can be attributed to their chemical composition [17][18][19][20] and organic content [21][22][23][24][25][26].…”
Section: Introductionmentioning
confidence: 99%
“…The main properties of peloids recognised are: their applications in thermotherapy [2,3,5,6] manifested by biological effects, metabolic and enzymatic activity, vascular, neuromuscular, analgesic and modifications of the viscoelastic properties of the tissues [7,8]; several other studies have confirmed their anti-inflammatory [9][10][11][12][13][14], chondroprotective [10,11] and immunological actions [10,[14][15][16] which can be attributed to their chemical composition [17][18][19][20] and organic content [21][22][23][24][25][26].…”
Section: Introductionmentioning
confidence: 99%
“…Indeed, decreased serum levels of proinflammatory mediators (PGE2, leukotriene B4, IL-1β, TNF-α, IL-8, IL-6, and eHsp72) and expression of microRNA related to cartilage degradation were observed after mud pack treatments in OA patients (Bellometti et al, 1998;Giannitti et al, 2017;Ortega et al, 2017;Maccarone et al, 2020). Interestingly, balneotherapy increased circulating cortisol concentration that enhanced monocyte chemotaxis to damaged tissue and their switch to an anti-inflammatory phenotype (Galvez et al, 2020).…”
Section: Balneotherapy On Oamentioning
confidence: 99%
“…(5), often encompassing rehabilitation objectives/procedures (6) (7). According to the definition given by the "International Society of Medical Hydrology", muds (peloids) and clays (8) are "substances formed in natural conditions under the influence of geological processes and which, mixed with water (9), are used in medical practice in the form of baths or local procedures (10). Muds are earths or rocks of a pasty consistency, used as therapeutic remedies or cosmetics (11) from remote times.…”
Section: Introductionmentioning
confidence: 99%
“…Some beneficial effects of mud are known empirically from antiquity, others have been described and studied quite recently, some have remained today in the stage of summary explanation. Mud treatment is also called pelotherapy (9), peloidotherapy, or sometimes -a largely -fango therapy. Pelotherapy should be used only as directed and under medical supervision (8).…”
Section: Introductionmentioning
confidence: 99%