Effect of Na⁺, K⁺ and Ca²⁺ Ions on Physico‐chemical Properties of Thymine, Cytosine, Thymidine and Cytidine in Aqueous Urea Solution

Abstract

Experimental determination of density, ultrasonic velocity and viscosity of two pyrimidine bases thymine and cytosine along with their respective nucleosides, thymidine and cytidine has been carried out in aqueous urea solutions in the presence of different concentrations of three salts, viz. NaCl, KCl and CaCl 2 . The experimental data have been used for the computation of various thermodynamic parameters, viz. apparent molar volume, apparent molar compressibility, coefficients A and B of the Jones-Dole equation, internal pressure, acoustic impedance, etc. Structural studies of solutions under investigation have also been carried out by ultraviolet spectroscopy, and an attempt has been made to collaborate the findings of ultraviolet spectroscopy with results obtained thermodynamically.

Interaction of 5-Chloro-2-hydroxy-3-nitroacetophenone in N,N-Dimethylformamide at Various Temperatures: A Viscometric, Volumetric and Ultrasonic Study

“…The knowledge of acoustical properties of pure liquid and liquid mixtures furnishes information on molecular structure, nature, and strength of molecular interactions. The physical and chemical properties of solutions and biomolecules have been studied by many workers [1][2][3][4] and evaluated thermodynamic and other related parameters with structural changes occurring in solutions with respect to variation in concentrations and temperatures. N,N-dimethylformamide (DMF) is a versatile solvent, used in the synthesis of pharmaceuticals, in agriculture chemistry, and serves as solvent for many polymers.…”