Effect of Naloxone on Blood Pressure Responses and Plasma Catecholamine Levels Following Clonidine Injection in Conscious, Unrestrained Rats

Naloxone and epinephrine are equally effective for cardiopulmonary resuscitation in a rat asphyxia model

“…An alternative hypothesis is the involvement of catecholamines and the autonomic nervous system. Naloxone can quickly stimulate catecholamine release (18–20), increase sympathetic nerve activity (21) and significantly elevate heart rate and blood pressure (22, 23). This could potentially improve the survival rate in the asphyxial rat model compared with the control group.…”