Effect of nano-reduction on properties of β-glucan and its use as encapsulating agent for release of α-tocopherol

β-Glucan from mushrooms and dates as a wall material for targeted delivery of model bioactive compound: Nutraceutical profiling and bioavailability

“…Moreover, in D-Glu and M−Glu stretching vibrations of C—O at 1025 and 1205 cm −1 were observed However, these bands showed lower intensity in En-Ru(D) and En-Ru(M).These positional changes in the peaks might be due to incorporation of the rutin within a carrier material [24] . Our results are in accordance with the previous study reported by Mei et al [8] which showed a similar result for encapsulation of rutin in lipid carrier. Remanan et al [21] and Natarajanet al [22] reported the similar behaviour of encapsulated rutin in carrier material.…”

“…To overcome such obstacles, rutin has been entrapped within different carriers like starch, egg albumin, olive oil, and liposomes [5] , [6] , [7] . Among different food grade delivery systems, β-glucan has gained focus as a wall material because of its honeycomb structure which can easily hold bioactive compounds resistance to heat, acid and enzymes, broad spectrum of biological activities and is a prebiotic [8] , [9] . The stability and harmless character of β-glucan makes it a GRAS substance certified by the FDA (US Food and Drug Administration) [8] .…”

“…Among different food grade delivery systems, β-glucan has gained focus as a wall material because of its honeycomb structure which can easily hold bioactive compounds resistance to heat, acid and enzymes, broad spectrum of biological activities and is a prebiotic [8] , [9] . The stability and harmless character of β-glucan makes it a GRAS substance certified by the FDA (US Food and Drug Administration) [8] . Further, the limitations of native β-glucan like low solubility, high viscosity, less bioavailability etc can be efficiently overcome by reducing its size as previously reported by Ashraf et al [8] : Ashraf et al [9] .…”

“…The stability and harmless character of β-glucan makes it a GRAS substance certified by the FDA (US Food and Drug Administration) [8] . Further, the limitations of native β-glucan like low solubility, high viscosity, less bioavailability etc can be efficiently overcome by reducing its size as previously reported by Ashraf et al [8] : Ashraf et al [9] . The structural variation of mushroom and date β-glucan results in difference in their properties.…”

“…The encapsulation efficiency was determined following the method described by Ashraf et al [8] . Encapsulated sample (50 mg) was washed using distilled water (5 mL) followed by centrifugation at 4000 rpm for 5 min.…”