Effect of nanoparticle macroalgae in the treatment of fatty liver disease using logistic regression, and support vector machine

Zheng, Nan; AL-Huqail, Arwa Abdulkreem; Lu, Yanjie; Ali, Elimam; Ali, H. Elhosiny; Zhao, Huajun

doi:10.1016/j.envres.2023.115426

Cited by 3 publications

(2 citation statements)

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“…Recently, marine milieu received more attention as a new sources of active components for enhancing the quality of diet against chronic diseases 20 . Some edible macroalgae such as Ascophyllum nodosum , Ecklonia cava , Ascophyllum nodosum and Fucus vesiculosus have been reported to contain large amounts of polyphenols in their structures 21–23 . Clinical studies also indicated that the consumption of edible seaweed may be effective against metabolic syndrome by modulating a variety of molecular signalling pathways 14,17,24 .…”

Section: Introductionmentioning

confidence: 99%

“… 20 Some edible macroalgae such as Ascophyllum nodosum , Ecklonia cava , Ascophyllum nodosum and Fucus vesiculosus have been reported to contain large amounts of polyphenols in their structures. 21 , 22 , 23 Clinical studies also indicated that the consumption of edible seaweed may be effective against metabolic syndrome by modulating a variety of molecular signalling pathways. 14 , 17 , 24 However, the effectiveness of these marine products have not been comprehensively evaluated.…”

Section: Introductionmentioning

confidence: 99%

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The effects of macro‐algae supplementation on serum lipid, glycaemic control and anthropometric indices: A systematic review and meta‐analysis of clinical trials

Rezaei

Doaei

Tabrizi

et al. 2023

Endocrino Diabet & Metabol

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IntroductionMacro‐algae products have been shown to ameliorate the metabolic disorders state. Thus, highlighting their function as supplementary therapeutic agents can be a novel strategy for clinical therapies. This systematic review and meta‐analysis of clinical trials aimed to summarize the effect of macro‐algae consumption on serum lipid profile, glycaemic control and anthropometric factors.MethodsIn this systematic review and meta‐analysis, a comprehensive search was performed for relevant studies published up to May 2023. The Cochran's Q test and I‐square (I2) tests were used to evaluate heterogeneity across the included studies. The meta‐analysis was conducted using random‐effects model (DerSimonian and Laird), and weighted mean difference (WMD) was considered as the pooled effect size.ResultsOut of 8602 papers in the initial screening, eight clinical trials with a total of 438 participants were included into this meta‐analysis. The results indicated that macro‐algae supplementation significantly decreased serum levels of total cholesterol (TC) (WMD = −6.7 mg/dL; 95% CI: −12.59, −0.80; item = 0.026) and low‐density lipoprotein cholesterol (LDL‐c) (WMD = −8.25 mg/dL; 95% CI: −15.38, −1.12; p‐value = .023). There was an increase in level of high‐density lipoprotein cholesterol (HDL‐c) (WMD = 0.48 mg/dL; 95% CI: −2.05, 3.01; p‐value = .71) which was not statistically significant. Macro‐algae supplementation reduced body mass index (BMI) (WMD = −0.28 kg/m2; 95% CI: −0.96, 0.41; p‐value = .426), weight (WMD = −0.39 kg; 95% CI: −3.6, 2.83; p‐value = .81), waist circumference (WC) (WMD = −0.52 cm; 95% CI: −2.71, 1.66; p‐value = .64), fasting blood sugar (FBS) (WMD = −1.95 mg/dL; 95% CI: −5.19, 1.28; p‐value = .24) and HbA1c (WMD = −0.02%; 95% CI: −0.14, 0.09; p‐value = .66) in intervention group.ConclusionsThis meta‐analysis indicated that macro‐algae supplementation significantly decreased TC and LDL‐c level. It can also increase HDL‐c level and reduce anthropometric indices and glycaemic control factors.

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Section: Introductionmentioning

confidence: 99%