Effect of nanosilica addition on bioactivity and in vivo properties of calcium aluminate cement

Calcium aluminate cement-based blends for application to fill in bone defects

“…However, tricalcium phosphate, chitosan, and collagen blends resulted lower values than bone "defect-free" based on the statistical difference, p < 0.05. Other study has shown that the mechanical strength of CAC using different types of a nano-silica increased with time reaching the necessary resistance for medical applications (Mohammadi et al 2019).…”

“…Calcium phosphate cement (CPC) is also a CBC and can be mixed with an aqueous liquid to form a paste that can be placed in the bone cavity to generate hydroxyapatite (Xu et al 2006;Chang et al 2020;Asadollahzadeh et al 2019;Liu et al 2019, Cárdenas-Balaguera;Gómez-Botero 2019). CAC-based biomaterials have similar chemistry to CPC-based bone cement and have been pointed out as a promising path for bone regeneration (Mohammadi et al 2019;Vasconcellos et al 2020).…”

“…Bioactive cements are one of the newest materials considered in medical engineering in the last decades; these cements are used as prostheses and implant stabilizers (Mohammadi et al 2019;Radwan et al 2017).…”

“…C u r r e n t l y , a l l b o n e c e m e n t s a r e b a s e d o n polymethylmethacrylate, PMMA, which has excellent mechanical properties but presents some deficiencies regarding its handling behavior and biocompatibility. Besides that, its setting-reactions are normally exothermic, thus generating excess heat, which can damage the surrounding tissue (Oréfice et al 2006;Engqvist et al 2008;Vasconcellos et al 2020;Mohammadi et al 2019). PMMA is not a bioactive material; it does not form a biological bonding with bone and does not generate apatite formation on its surfaces when treated with simulated body fluid (SBF) solution (Alves et al 2006;Oliveira et al 2017).…”

Effect of CaCO3 nanoparticles on the microstructure and fracture toughness of ceramic nanocomposites

“…Singh et al [20] reported that adding 4 wt% SiO 2 nanoparticles into epoxy polymer composites improved the tensile strength and flexural strength by 30.57% and 17%, consecutively, compared to the control epoxy composite. Moreover, various nanomaterials have been employed in ceramics and concrete, such as nano-SiO 2 , nano-ZnO, nano-TiO 2 , nano-Al 2 O 3 , or carbon nanotubes, to improve the physical and chemical properties of those materials or composites [21][22][23]. Meddah et al [24] examined the influence of Al 2 O 3 nanoparticles with different ratios on the mechanical properties of concrete nanocomposites.…”