Effect of negative valence on assessment of self-relevance in female patients with borderline personality disorder

Sarkheil, Pegah; Goik, Niko; Ibrahim, Camellia N.; Schneider, Frank

doi:10.1371/journal.pone.0209989

Cited by 8 publications

(9 citation statements)

References 41 publications

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“…Reduced functional connectivity between the DMN and occipital areas may be associated with an inflexible integration of sensory stimuli into self-referential processing in patients with BPD ( Wolf et al, 2011 ). A disturbed SR for negative statements in BPD has been indicated in previous literature ( Sarkheil et al, 2019 ). Our finding about reduced functional connectivity between the PCC and the occipital cortex for SR ratings of negative sentences provide additional evidence about SR is affected by negative contents in patients with BPD.…”

Section: Discussionmentioning

confidence: 56%

“…In a previous study, we demonstrated a higher SR for negative sentences in female patients with BPD compared to healthy controls (HC). We also uncovered a positive correlation between the SR for negative sentences and the severity of BPD symptoms ( Sarkheil et al, 2019 ). Apart from this, most investigations of self-related processing in BPD have focused largely on the evaluation of self-esteem, revealing low ( Bungert et al, 2015 , Lynum et al, 2008 ) or unstable ( Hochschild Tolpin et al, 2004 ) self-esteem in this group of patients.…”

Section: Introductionmentioning

confidence: 81%

“…Delineating the neural correlates of SR evaluation in the brain can provide key insights into the physiological basis of behavior in general and the SR-related pathologies in particular. The clinical reports about aberrant judgements of SR in BPD ( Bender and Skodol, 2007 , Jørgensen, 2006 , Sarkheil et al, 2019 ) and the importance of SR biases in treatment strategies ( Lin et al, 2018 ) serve as a motivation for further explorations of disorder-specific neural alterations. To this end, we adopted an ROI approach as the next exploratory step.…”

Section: Discussionmentioning

confidence: 99%

“…Neural correlates of altered SR involving the CMS and the MNS have been reported in psychiatric diseases such as schizophrenia, autism spectrum disorder and unipolar depression ( Zhao et al, 2013 ). Although evidence suggests that individuals with BPD exhibit a deviant appraisal of SR ( Sarkheil et al, 2019 , Sauer et al, 2014 , Winter et al, 2015a ), neural correlates of SR have yet to be investigated in this group of patients. Given the importance of self-related disturbances in the BPD psychopathology, neuroimaging studies that focus on the processing of SR are particularly well-suited for facilitating symptom stratification measures and treatment development.…”

Section: Introductionmentioning

confidence: 99%

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Altered functional connectivity during evaluation of self-relevance in women with borderline personality disorder

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Ibrahim

et al. 2020

NeuroImage: Clinical

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Highlights: Appraisal of self-relevance is disturbed in borderline personality disorder (BPD). We introduce the first neuroimaging study about self-relevance processing in BPD. Besides the CMS, the MNS and the SMA are involved in self-relevance processing. Functional connectivity of CMS is altered in BPD during self-relevance evaluations. In BPD, valence affects the functional connectivity during self-relevance ratings.

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Section: Discussionmentioning

confidence: 56%

Section: Introductionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Altered functional connectivity during evaluation of self-relevance in women with borderline personality disorder

Orth

Zweerings

Ibrahim

et al. 2020

NeuroImage: Clinical

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“…However, there were no differences in the Shame-IAT between healthy women and female patients with social phobia as compared to women with BPD in another study (Rüsch et al, 2007). Because a general negative evaluation bias for self-referential and self-relevant information is important in BPD and increases with its severity (Sarkheil et al, 2019; Winter et al, 2017), it may well be that our findings reflect a general association of BPD with any negative emotion or trait. This is particularly true as we included in-patients with BPD suffering from severe BPD pathology, for example, compared to BPD outpatients.…”

Section: Discussionmentioning

confidence: 79%

Negative self-conscious emotions in women with borderline personality disorder as assessed by an Implicit Association Test.

Spitzer

Jelinek

Baumann

et al. 2021

Personality Disorders: Theory, Research, and Treatment

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Shame and guilt are vital in borderline personality disorder (BPD), and previous research using explicit measures has consistently found elevated levels of these self-conscious emotions (SCE) in those with BPD. However, these measures cannot elucidate implicit processes that are equally important, as they guide the perceptions of the self and influence behavioral responses. Thus, we aimed to extend the research on SCE in BPD utilizing an indirect latency-based measure. A total of 29 female inpatients with BPD and 21 healthy women were assessed with a shame and a guilt self-concept Implicit Association Test (IAT). These two tasks use reaction time measurements to determine the relative strengths of associations between the self versus others and shame versus pride and guilt versus innocence. In addition, participants completed questionnaires capturing shame, guilt, and BPD symptoms. Women with BPD displayed significantly more shame-and guilt-prone implicit self-concepts than the control group (d ϭ 1.2 and d ϭ 0.7, respectively). They also scored significantly higher on explicit measures of shame and guilt. Although explicitly and implicitly assessed shame and guilt were strongly associated with borderline pathology, multivariate models indicated that solely self-reported, but not implicitly measured, guilt was consistently related to all BPD outcomes. Shame was only associated with the number of BPD criteria. This study extends previous findings on SCE in BPD, in that women with BPD do not only explicitly conceive themselves as more shame-and guilt-prone but also exhibit implicitly more shame and guilt self-concepts than healthy controls. Our results may hold clinical and therapeutic implications.

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Differential diagnosis of borderline personality disorder and bipolar disorder: Self‐concept, identity and self‐esteem

Wright

Lari

Iazzetta

et al. 2021

Clin Psychology and Psychoth

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Symptoms of borderline personality disorder (BPD) and bipolar disorder (BD) often overlap. In some cases, it is difficult to conduct a differential diagnosis based only on current diagnostic criteria Therefore, it is important to find clinical factors with high discriminatory specificity that, used together with structured or semi‐structured interviews, could help improve diagnostic practice. We propose that a clinical analysis of identity, self‐concept and self‐esteem may help distinguish the two disorders, when they are not co‐morbid. Our review of the studies that analyse these constructs in BD and BPD, separately, points in the direction of qualitative differences between the two disorders. In BPD, there is a well‐documented identity diffusion, and the self‐concept appears predominantly negative; shifts in self‐concept and self‐esteem are often tied to interpersonal triggers. In BD, patients struggle with their identity, but narrative identity might be less compromised compared with BPD; the shifts in self‐concept and self‐esteem appear more linked to internal (i.e. mood and motivational) factors. We end the paper by discussing the implications for clinicians and ideas for future comparative research.

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Effect of negative valence on assessment of self-relevance in female patients with borderline personality disorder

Cited by 8 publications

References 41 publications

Altered functional connectivity during evaluation of self-relevance in women with borderline personality disorder

Altered functional connectivity during evaluation of self-relevance in women with borderline personality disorder

Negative self-conscious emotions in women with borderline personality disorder as assessed by an Implicit Association Test.

Differential diagnosis of borderline personality disorder and bipolar disorder: Self‐concept, identity and self‐esteem

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