Effect of Neonatal Hyperbilirubinemia on Ventricular Functions

Abstract

Objectives: Unconjugated hyperbilirubinemia is a common systemic disease in neonates. Many studies on etiology, risk factors, and treatment have been conducted, and guidelines have been established. Because unconjugated hyperbilirubinemia is a systemic disease, it affects the body, cells, cellular organelles, organs, and systems. Studies have also attempted to clarify the levels, mechanisms, and organs affected by unconjugated bilirubin. We aimed to investigate the effect of high unconjugated bilirubin levels on the left and right ventricular systolic and diastolic functions in newborns by echocardiography and Doppler. Materials and Methods: This observational retrospectivecohort study evaluated neonates with hyperbilirubinemia requiring treatment according to the American Academy of Pediatrics guidelines, who were Results: There was no correlation between the serum total bilirubin levels and the echocardiographic measures.Conclusions: In our study, unconjugated hyperbilirubinemia did not affect the left and right ventricular functions.

Effect of Phototherapy on Cardiac Functions in Neonates with Hyperbilirubinemia. A Prospective Cross-Sectional Study

“…Phototherapy Karabulut B et al 2019 [19] found no significant differences between the cases and controls in EF, FS, LVEDd, and LVEDs. They also discovered no statistically significant variations in mitral, tricuspid, septal E', A', and S' across groups.…”