Effect of Ni substitution and annealing temperature on structural and magnetic properties of MnZn-Ferrites: Cytotoxicity study of ZnO and SiO2 coated core shell structures

Mallesh, Shanigaram; Mondal, Pradip Kumar; Kavita, S.; Srinivas, V.; Nam, Young-Woo

doi:10.1016/j.apsusc.2022.154648

Cited by 11 publications

(1 citation statement)

References 49 publications

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“…As depicted in Figure g, the diffraction patterns revealed distinct peaks corresponding to crystallographic planes. These peaks can be attributed to the spinel structure of Mn 0.5 Zn 0.5 Fe 2 O 4 . , Notably, the diffraction peak associated with the multi-walled carbon nanotubes (MWCNTs) was not observed, suggesting a low concentration of MWCNTs in the nanohybrids. Furthermore, no peaks indicative of crystalline impurities were detected, affirming the synthesis of high-purity Mn–Zn ferrite with good crystallinity. , …”

Section: Resultsmentioning

confidence: 99%

Multiwalled Carbon Nanotubes Decorated with Mn_0.5Zn_0.5Fe₂O₄ Nanoparticles for Magneto-Photothermal Cancer Therapy

Shen

Yan

Xue

et al. 2023

ACS Appl. Nano Mater.

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Alternative cancer treatments such as photothermal therapy (PTT) and magnetic hyperthermia (MHT) techniques have been studied to show promising potential as supplementary modalities. However, such techniques have their own limitations; for instance, highly concentrated intratumoral injections of magnetic nanoparticles are required to compensate their low specific loss power under safe and low magnetic field intensity for the MHT, while the PTT has limitations in the treatment of deep-seated tumors due to low light penetration. Here, the decoration of the multi-walled carbon nanotube (MWCNT) surface by magnetic nanoparticles (≈8.5 nm) was achieved by a hydrothermal method and the development of MWCNT/Mn0.5Zn0.5Fe2O4 (MZFC) hybrids for magneto-photothermal dual-mode cancer therapy. The obtained specific loss power of the MZFC hybrids is found to be at least 1 order of magnitude higher, with improvement from ∼19 W/g to 225 W/g, under the excitation of both an AMF with a magnetic field intensity of 6.4 kA/m and a frequency of 300 kHz and a simultaneous NIR laser of 0.5 W/cm2 irradiation. The synergistic utilization of the photothermal and magnetic properties of MZFC effectively diminishes the required magnetic field amplitude and NIR laser power density. Our in vitro cell experiments confirmed that the thermal effects mediated by the MZFC after endocytosis delivered enhanced cytotoxicity in the presence of dual excitation of NIR laser and AMF. These findings indicate that MZFC nanohybrids possess significant potential as targeted nanoheating agents for hyperthermia applications.

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Section: Resultsmentioning

confidence: 99%

Multiwalled Carbon Nanotubes Decorated with Mn_0.5Zn_0.5Fe₂O₄ Nanoparticles for Magneto-Photothermal Cancer Therapy

Shen

Yan

Xue

et al. 2023

ACS Appl. Nano Mater.

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Functional Magnetic Nanoparticles for Drug Delivery Application

Praharaj,

Rout

2024

Functionalized Magnetic Nanoparticles for Theranostic Applications

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Studies on Re-188 Labeling and In Vivo Distribution of Magnetic Nanoparticles with Different Morphologies and Sizes

Huang,

Zhao,

Yang

et al. 2023

J Inorg Organomet Polym

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There has been few research on the affect and distribution of different shapes of nanoparticles inside an organism during extraction and drug targeting. In order to obtain the distribution of magnetic nanoparticles with different morphology and size in vivo, a general method of Re-188 labeled Magnetic Core-Shell Nanoparticles (MNPs) Materials was developed. Based on the prepared magnetic particles with three different morphologies and sizes, including 230 nm spherical Fe 3 O 4 @SiO 2 particles (S-230), 100 nm spherical Fe 3 O 4 @SiO 2 particles (S-100) and peanut shaped Fe 3 O 4 @SiO 2 particles (P-180,the length of the short axis is about 100 nm and the length of the long axis is about 180 nm),the aminated MNPs were labeled with radionuclide Re-188 through the coupling of diethylenetriamine pentaacetic anhydride (DTPAA). The nuclide Re-188 was labeled to investigate their distribution behavior in mice. Most of the small-size particles S-100 can be separated from the capture of the endothelial reticular system and removed by renal metabolism. Most of the larger particles, S-230 and P-180, will be captured by the endothelial reticular system, and the nanoparticles P-180 with large aspect ratio are easier to be captured by the tissue in the spleen and enter the cells through endocytosis.

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Effect of Ni substitution and annealing temperature on structural and magnetic properties of MnZn-Ferrites: Cytotoxicity study of ZnO and SiO2 coated core shell structures

Cited by 11 publications

References 49 publications

Multiwalled Carbon Nanotubes Decorated with Mn_0.5Zn_0.5Fe₂O₄ Nanoparticles for Magneto-Photothermal Cancer Therapy

Multiwalled Carbon Nanotubes Decorated with Mn_0.5Zn_0.5Fe₂O₄ Nanoparticles for Magneto-Photothermal Cancer Therapy

Functional Magnetic Nanoparticles for Drug Delivery Application

Studies on Re-188 Labeling and In Vivo Distribution of Magnetic Nanoparticles with Different Morphologies and Sizes

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Effect of Ni substitution and annealing temperature on structural and magnetic properties of MnZn-Ferrites: Cytotoxicity study of ZnO and SiO2 coated core shell structures

Cited by 11 publications

References 49 publications

Multiwalled Carbon Nanotubes Decorated with Mn0.5Zn0.5Fe2O4 Nanoparticles for Magneto-Photothermal Cancer Therapy

Multiwalled Carbon Nanotubes Decorated with Mn0.5Zn0.5Fe2O4 Nanoparticles for Magneto-Photothermal Cancer Therapy

Functional Magnetic Nanoparticles for Drug Delivery Application

Studies on Re-188 Labeling and In Vivo Distribution of Magnetic Nanoparticles with Different Morphologies and Sizes

Contact Info

Product

Resources

About

Multiwalled Carbon Nanotubes Decorated with Mn_0.5Zn_0.5Fe₂O₄ Nanoparticles for Magneto-Photothermal Cancer Therapy

Multiwalled Carbon Nanotubes Decorated with Mn_0.5Zn_0.5Fe₂O₄ Nanoparticles for Magneto-Photothermal Cancer Therapy