2019
DOI: 10.1007/s12020-019-01963-4
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Effect of Nigella Sativa oil versus metformin on glycemic control and biochemical parameters of newly diagnosed type 2 diabetes mellitus patients

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Cited by 36 publications
(35 citation statements)
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“…Nigella sativa was inferior to metformin in terms of lowering FPG, 2 h postprandial glucose, and A1C. However, NS was comparable to metformin in lowering the body weight, waist circumference, and BMI significantly and was well tolerated with no side effects [39].…”
Section: Discussionmentioning
confidence: 87%
“…Nigella sativa was inferior to metformin in terms of lowering FPG, 2 h postprandial glucose, and A1C. However, NS was comparable to metformin in lowering the body weight, waist circumference, and BMI significantly and was well tolerated with no side effects [39].…”
Section: Discussionmentioning
confidence: 87%
“…Studies suggest a bene cial effect of N. sativa supplementation on glycemic status, especially fasting blood glucose and HbA1c [24,28]. Also, a hypolipidemic effect of N. sativa was shown by reducing verylow-density lipoprotein, triglyceride, total cholesterol, and low-density lipoprotein level [28,40,41].…”
Section: Discussionmentioning
confidence: 99%
“…Various types of plants and nutrients with health-improving properties have been identi ed due to their anti-in ammatory, lipid-lowering, anti-hypertensive and antioxidant properties, which can be potential interventions for cardiovascular disease [3,23,24]. Nigella sativa, which is also recognized as Black seed, is one of the medicinal plants that was used traditionally in the treatment of a wide range of conditions such as asthma, diarrhea, bloating [25][26][27].…”
mentioning
confidence: 99%
“…Moreover, in a randomized F I G U R E 6 Forest plot of the mean difference for the effect of NS consumption on serum SOD levels preliminary study, the twice-daily administration for 3 months of two capsules containing 500 mg of NS in patients with oral submucous fibrosis was accompanied by a significantly increase in SOD levels (Pipalia et al, 2016). On the contrary, Moustafa et al (2019) reported no significant reduction in serum TAC levels after 3 g/ day of NS administration for 3 months in type 2 diabetes mellitus patients. Furthermore, in another study recruiting epileptic children, the administration of 40-80 mg kg −1 day −1 of black seed did not change TAC and MDA levels significantly as compared to placebo (Shawki et al, 2013).…”
Section: F I G U R Ementioning
confidence: 99%