Effect of nitride film coatings on cell compatibility

Chien, Chia‐Chi; Liu, Kuan‐Ting; Duh, Jenq Gong; Chang, Kuo Wei; Chung, Kwok Hung

doi:10.1016/j.dental.2007.11.020

Cited by 67 publications

(43 citation statements)

References 36 publications

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“…Brama et al reported that TiN has superior biological properties compared to other nitrides [5]. Another biocompatible nitride is TiAlN, which proved to be a good candidate for the biomedical applications despite its Al content [3]. Some researchers proved that the transition metal carbonitride coatings increased the service life of orthopedic implants, especially in terms of wear resistance in the biological environments [60][61][62][63][64][65].…”

Section: Bioinert Coatingsmentioning

confidence: 98%

“…In this group, oxides, nitrides, oxynitrides, carbonitrides, and carbide were found. Many different transition metal nitride (TiN, TiAlN, ZrN, NbN [3,4]), carbide (TiC [5]), oxide (ZrO2 [6], TiO 2 [7]), or oxynitride (TiON [8]) coatings have a wide application as biomaterials, due to their valuable properties such as high hardness, better wear and corrosion resistance, and good biocompatibility. Bioactive coatings are those which, after the implantation, guarantee a good interaction with the bone by enhancement adhesion between the bone and implant.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Bioceramic Coatings for Metallic Implants

Vlădescu

Surmeneva

Cotruț

et al. 2016

Handbook of Bioceramics and Biocomposites

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Section: Bioinert Coatingsmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Bioceramic Coatings for Metallic Implants

Vlădescu

Surmeneva

Cotruț

et al. 2016

Handbook of Bioceramics and Biocomposites

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“…Chien et al [17] used primary human gingival fibroblast and reported significant increase in proliferation of cells cultured on TiN and TiAlN coated surfaces as compared to the uncoated surfaces of Ni-based alloy. Also these cells did not show cytotoxicity when they were cultured on TiN or TiAlN coated surfaces.…”

Section: Introductionmentioning

confidence: 98%

“…Also these cells did not show cytotoxicity when they were cultured on TiN or TiAlN coated surfaces. Thus TiAlN coating has the potential to support tissue growth on dental implant surfaces [17].…”

Section: Introductionmentioning

confidence: 99%

Surface characteristics and osteoblast cell response on TiN- and TiAlN-coated Ti implant

Jang¹,

Ha²,

Kim³

et al. 2011

Biomed. Eng. Lett.

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Purpose The purpose of this study was to evaluate the surface characteristics and osteoblast cell response of TiN and TiAlN coated on Ti Surface. Methods TiN and TiAlN coatings were applied on Ti dental implant and surface characteristics of these coatings were evaluated. And osteogenic effect of TiN and TiAlN coating on MG63 osteoblast-like cell proliferation and differentiation was evaluated by cell viability assay (MTT assay), ALP activity assay and expressions of collagen gene. Results As observed by SEM, both the TiN and TiAlN coatings had thickness of about 1.7 µm. From the EDX analysis, Ti and N peaks and Ti, Al and N peaks are confirmed on the TiN and TiAlN coating surface, respectively. The wetting angles of TiN and TiAlN coatings were increased as compared to that of control Ti. As compared to Ti, a great number of attached cells on TiN and TiAlN coated surfaces were observed. The cell survival rate of the TiN and TiAlN were 125% and 117% as compared to that of the Ti (100%). Both the TiN and TiAlN coatings produced equivalent levels of protein. ALP activity of MG63 cells grown on Ti, TiN and TiAlN surface is indicated. Collagen gene was overexpressed in cells cultured on TiN and TiAlN in comparison with the Ti.Conclusions TiN and TiAlN coatings on Ti dental implant may have potential for use in dental implant in terms of their biocompatibility.

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“…Biocompatibility of the TiN coating to its oral surroundings is also very important clinically. Chien et al [27] evaluated the cytotoxicity of nickel-based alloy surfaces after nitride film coatings of TiN and TiAlN. At 3 h, human fibroblast cells began to spread across all test surfaces, but at 24 h, the coated groups were significantly higher in cell proliferation and viability than polished and control Ni-alloy surfaces.…”

Section: Coatings In Prosthodonticsmentioning

confidence: 99%

Titanium Nitride and Nitrogen Ion Implanted Coated Dental Materials

et al. 2012

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Titanium nitride and/or nitrogen ion implanted coated dental materials have been investigated since the mid-1980s and considered in various applications in dentistry such as implants, abutments, orthodontic wires, endodontic files, periodontal/oral hygiene instruments, and casting alloys for fixed restorations. Multiple methodologies have been employed to create the coatings, but detailed structural analysis of the coatings is generally lacking in the dental literature. Depending on application, the purpose of the coating is to provide increased surface hardness, abrasion/wear resistance, esthetics, and corrosion resistance, lower friction, as well as greater beneficial interaction with adjacent biological and material substrates. While many studies have reported on the achievement of these properties, a consensus is not always clear. Additionally, few studies have been conducted to assess the efficacy of the coatings in a clinical setting. Overall, titanium nitride and/or nitrogen ion implanted coated dental materials potentially offer advantages over uncoated counterparts, but more investigation is needed to document the structure of the coatings and their clinical effectiveness. OPEN ACCESSCoatings 2012, 2 161

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Effect of nitride film coatings on cell compatibility

Cited by 67 publications

References 36 publications

Bioceramic Coatings for Metallic Implants

Bioceramic Coatings for Metallic Implants

Surface characteristics and osteoblast cell response on TiN- and TiAlN-coated Ti implant

Titanium Nitride and Nitrogen Ion Implanted Coated Dental Materials

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