“…Early (within 7 days from symptom onset) initiation of antiviral therapy may be critical in reducing SARS-CoV-2 viral load, as previously noted ( Fu et al, 2020 , Keyaerts et al, 2004 , Yan et al, 2020a , Yan et al, 2020b ). Due to the limitation of our database, it was difficult to know the initiation timing of antiviral treatment in each individual patient; however, the government of South Korea had launched a series of aggressive measures to perform tight contact tracing and mass screening tests, which enabled early diagnosis within 3–5 days from symptom onset ( Ryu et al, 2020 ). Based on the expert’s guideline, most patients were treated within 7 days after symptom development ( Kim et al, 2020 ).…”