Colossal magnetoresistance (CMR) and electroresistance (CER) induced by the electric field in spinel multiferroic CdCr 2 S 4 are reported. It is found that a metal-insulator transition (MIT) in CdCr 2 S 4 is triggered by the electrical field. In magnetic fields, the resistivity of CdCr 2 S 4 responds similarly to that of CMR manganites. Combing previous reports, these findings make CdCr 2 S 4 the unique compound to possess all four properties of the colossal magnetocapacitive (CMC), colossal electrocapacitive (CEC), CER, and CMR. The present results open a new venue for searching new materials to show CMR by tuning electric and magnetic fields.