Effect of norepinephrine on renal tubular NaKATPase and oxygen consumption

Effects of norepinephrine on renal perfusion, filtration and oxygenation in vasodilatory shock and acute kidney injury

“…However, RVO 2 was not higher in the present study, despite the higher GFR and renal sodium reabsorption. The explanation for this disparity is not obvious, but it has been shown that NE causes an a 1 -mediated increase in proximal tubular sodium transport with no effect on cellular oxygen consumption [35].…”