Spherical CdSe-ZnS quantum dots are promising materials for optoelectronic applications. This study explores the impact of varying core-shell radii ratios on the confinement energy and optoelectronic properties of these quantum dots, utilizing the Time-Independent Schrödinger Equation to model these effects. Simulations were conducted for core-to-shell ratios from 1.5:1 to 4:1, revealing that higher ratios – achieved by reducing core radii or expanding shell radii – significantly enhance quantum confinement, with electron confinement energy observed to increase from 0.1 eV to 2.2 eV across the range of ratios. Transition energy calculations indicate well-aligned electron and hole energy gaps, which lead to increased oscillator strengths, thereby optimizing optical properties. These results provide valuable insights into the design of quantum dot structures tailored for improved performance in LEDs, photovoltaic cells, and other optoelectronic applications.