Effect of opium use on short-term outcome in patients undergoing coronary artery bypass surgery

Safaii, N; Kazemi, Babak

doi:10.1007/s11748-009-0529-7

Cited by 29 publications

(31 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a historical cohort study of 110 patients addicted to opium over 1.5 years, Nemati et al 33 reported a significant increase in hemorrhage and blood transfusions after CABG, consistent with our findings. A prospective review of 56 opium-using patients conducted by Safaii and Kazemi 17 reported no difference in mortality and comparable complication rates (pulmonary complications, 14.2%; blood transfusions, 33.3%), but complications did not significantly differ between opium users and nonusers. It is important to note that the population studied differs from ours in that opium use in the Middle East may not directly translate to the opioid-type drugs used in the United States.…”

Section: Discussionmentioning

confidence: 97%

Trends and Outcomes of Cardiovascular Surgery in Patients With Opioid Use Disorders

Dewan

Idrees

et al. 2019

JAMA Surg

View full text Add to dashboard Cite

IMPORTANCE Persistent opioid use is currently a major health care crisis. There is a lack of knowledge regarding its prevalence and effect among patients undergoing cardiac surgery. OBJECTIVE To characterize the national population of cardiac surgery patients with opioid use disorder (OUD) and compare outcomes with the cardiac surgery population without OUD. DESIGN, SETTING, AND PARTICIPANTS In this retrospective population-based cohort study, more than 5.7 million adult patients who underwent cardiac surgery (ie, coronary artery bypass graft, valve surgery, or aortic surgery) in the United States were included. Pregnant patients were excluded. Propensity matching was performed to compare outcomes between cardiac surgery patients with OUD (n = 11 359) and without OUD (n = 5 707 193).

show abstract

Section: Discussionmentioning

confidence: 97%

Trends and Outcomes of Cardiovascular Surgery in Patients With Opioid Use Disorders

Dewan

Idrees

et al. 2019

JAMA Surg

View full text Add to dashboard Cite

show abstract

“…But findings of Sadeghian et al[14]’s research on 4398 isolated CABG patients and opium dependence rate of 15.6%, found no relationship between post CABG in hospital complications and opium addiction. But on the other hand, in a study conducted by Safaii et al[15] on 6-mo outcomes of CABG patients, opium usage leaded to more readmission following CABG operation.…”

Section: Discussionmentioning

confidence: 97%

“…In a propensity-matched study, Sadeghian et al[14] found no association between opium dependence and post CABG in-hospital complications. On the other hand, in Safaii et al[15]’s study, six months post-CABG readmission was significantly more frequent in opium users. However, there are few evidences to clarify the definite relationship between chronic opium abuse and long-term survival in cardiac surgery patients.…”

Section: Introductionmentioning

confidence: 87%

Outcomes and long-term survival of coronary artery surgery: The controversial role of opium as risk marker

Najafi

Jahangiry

Mortazavi

et al. 2016

WJC

View full text Add to dashboard Cite

AIMTo study survival in isolated coronary artery bypass graft (CABG) patients and to evaluate the impact of preoperative chronic opium consumption on long-term outcome.METHODSCohort of 566 isolated CABG patients as Tehran Heart Center cardiac output measurement was conducted. Daily evaluation until discharge as well as 4- and 12-mo and 6.5-year follow-up information for survival status were fulfilled for all patients. Long-term 6.5-year overall and opium-stratified survival, adjusted survival curves based on opium consumption as well as possible predictors of all-cause mortality using multiple cox regression were determined by statistical analysis.RESULTSSix point five-year overall survival was 91.8%; 86.6% in opium consumers and 92.7% in non-opium consumers (P = 0.035). Patients with positive history of opium consumption significantly tended to have lower ejection fraction (EF), higher creatinine level and higher prevalence of myocardial infarction. Multiple predictors of all-cause mortality included age, body mass index, EF, diabetes mellitus and cerebrovascular accident. The hazard ratio (HR) of 2.09 for the risk of mortality in opium addicted patients with a borderline P value (P = 0.052) was calculated in this model. Further adjustment with stratification based on smoking and opium addiction reduced the HR to 1.20 (P = 0.355).CONCLUSIONSimultaneous impact of smoking as a confounding variable in most of the patients prevents from definitive judgment on the role of opium as an independent contributing factor in worse long-term survival of CABG patients in addition to advanced age, low EF, diabetes mellitus and cerebrovascular accident. Meanwhile, our findings do not confirm any cardio protective role for opium to improve outcome in coronary patients with the history of smoking. Further studies are needed to clarify pure effect of opium and warrant the aforementioned findings.

show abstract

“…11 A somewhat similar effect has been reported after total hip and knee arthroplasty and CABG but this needs more investigation. 12,13 Studies have shown a significant link between unemployment and risk of blood transfusion in spine surgery patients, increased LOS and decreased health-related quality of life after surgery. 4,14,15 We add that unemployment status in spinal surgery patients is associated with higher comorbidity rates which consume additional healthcare resources.…”

Section: Discussionmentioning

confidence: 99%

Higher comorbidity rates in unemployed patients may significantly impact the cost of spine surgery

Walid

Robinson

Robinson³

2011

Journal of Clinical Neuroscience

View full text Add to dashboard Cite

Effect of opium use on short-term outcome in patients undergoing coronary artery bypass surgery

Abstract: Continued use of opium is a significant predictor of rehospitalization with a cardiac cause within 6 months of CABG surgery. This may be partly due to the low compliance of these patients with treatment recommendations.

Cited by 29 publications

References 22 publications

Trends and Outcomes of Cardiovascular Surgery in Patients With Opioid Use Disorders

Trends and Outcomes of Cardiovascular Surgery in Patients With Opioid Use Disorders

Outcomes and long-term survival of coronary artery surgery: The controversial role of opium as risk marker

Higher comorbidity rates in unemployed patients may significantly impact the cost of spine surgery

Contact Info

Product

Resources

About