Effect of oral administration of tormentil root extract (Potentilla tormentilla) on rotavirus diarrhea in children: a randomized, double blind, controlled trial

Abstract

The administration of tormentil root extract in controlled doses shortened the duration of rotavirus diarrhea and decreased the requirement for rehydration solutions. Tormentil root extract appears to be an effective measure to treat rotavirus diarrhea in children.

Acute Diarrheal Disease in Children: Epidemiology, Prevention, and Treatment

“…Research on developing new ORS that would decrease the volume of loose stools is ongoing. Probiotics and other natural products that may have an effect on shortening episodes of acute infectious diarrhea are being studied [51,52]. Finally, prevention of diarrheal diseases by immunization is desirable.…”

Potentilla—A review of its phytochemical and pharmacological profile

“…In a randomized, double blinded, placebo-controlled clinical trial Russian authors (Subbotina et al, 2003) have shown a high efficacy of a Potentilla erecta rhizome dry extract (one part of dried root with 10 parts of 40% ethanol, 30-40% of tannins, saponin and other components) in child diarrhoea therapy due to a Rotavirus infection (Subbotina et al, 2003). Forty children (20 verum-and 20 placebo-treated) were enrolled.…”

“…In parallel pharmacological (in vitro and in vivo) evaluations of Potentilla species and their extracts were put forward especially since the 1980s. Within the last years first clinical studies were performed for Potentilla erecta rhizome extracts for the treatment of colitis ulcerosa (Huber et al, 2007) and also for the treatment of virus-induced diarrhoea in children (Subbotina et al, 2003).…”

Management of Acute Gastroenteritis in Children: A Systematic Review of Anthroposophic Therapies

“…Experienced anthroposophic pediatricians recommended this remedy for children suffering from rotavirus enteritis [28]. A shortening of duration and a decrease of rehydration solution requirements in children with rotavirus diarrhea was also demonstrated in a randomized, double-blinded, placebo-controlled trial encompassing 40 patients [51] (table 4). …”