Effect of parathyroid feeding on the thyroid

Abstract

Two hypotheses have been put forward to explain the relationship of the thyroid and parathyroid. The The following experiments were carried out to show the effect of parathyroid feeding on the structure of the thyroid, and hence obtain information with regard to the functional relationship of the two glands.Very few experiments correlating the respective functions and structure of the thyroid and parathyroid havebeen carried out. K oj im a (6) fed rats with parathyroid but his results are not satisfactory as the rats had previously been fed with thyroid. Halpenny and Thompson (2) give diagrams which indicate that after parathyroidectomy the vesicles of the thyroid are larger, more irregular, and appear more active.Methods. Adult and young rats of both sexes were used for these experiments.

The parathyroids.

“…Colloid is scarce and the cells tend to arrange themselves in columns, separated by bands of connective tissue. Each gland has a well defined capsule (2,8,9,65,96,106,123).It has been held that the thyroid and parathyroids are closely related functionally, that the latter are merely embryonic thyroid tissue (118). The beautiful researches done on parathyroid tetany seem to show conclusively that, although their association is an intimate one from the standpoint of location, functionally the two organs are quite distinct (47,48,51,54,55).Function.…”

“…Colloid is scarce and the cells tend to arrange themselves in columns, separated by bands of connective tissue. Each gland has a well defined capsule (2,8,9,65,96,106,123).…”

“…Such evidence Collip interprets as antagonistic to the guanidin toxemia theory. However, some of Luckhardt's work, which will be discussed later, suggests that the toxemia theory has not been entirely disposed of (3,13,62,80,94,97,98,103,104,105,119,123).…”