Effect of Partially Protected Sodium Butyrate on Performance, Digestive Organs, Intestinal Villi and E. coli Development in Broilers Chickens

Chamba, F.; Puyalto, Mónica; Ortiz, Álvaro; Torrealba, Hector; Mallo, J. J.; Riboty, R.

doi:10.3923/ijps.2014.390.396

Cited by 68 publications

(53 citation statements)

References 18 publications

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“…Many studies have been published about different additives’ effects on broiler chicken performance and immune response when challenged with Escherichia coli K88, such as prebiotics, probiotic, short-chain fatty acids, and essential oils, but little is known about polysaccharide additives [4,5,6,7]. These additives promote growth performance by increasing the average daily feed intake and improving immune function and intestinal villi development, but there has been very little research on the effects on the intestinal microbial community structure and balance of the host [8,9].…”

Section: Introductionmentioning

confidence: 99%

Effects of Achyranthes bidentata Polysaccharides on Intestinal Morphology, Immune Response, and Gut Microbiome in Yellow Broiler Chickens Challenged with Escherichia coli K88

Liu

Wang

et al. 2018

Polymers

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The present study was conducted to investigate the effects of dietary Achyranthes bidentata polysaccharide (ABPS) supplementation on performance, immune response, intestinal mucosal morphology, and gut microbiome in yellow-feathered broilers challenged with Escherichia coli K88. A 2 × 2 factorial design was used for the trial. Two hundred and forty one-day-old female broilers were randomly assigned to four treatments: (1) negative-control broilers were fed by a basal diet and saline (NG); (2) positive-control broilers were fed by a basal diet and orally challenged with 108 CFU E. coli K88 (CNG); (3) ABP group broilers were fed by a basal diet containing ABPS (500 mg/kg of feed) and saline; (4) CABP group broilers were fed by a basal diet containing ABPS (500 mg/kg of feed) and orally challenged with 108 CFU E. coli K88. Growth performance, serum biochemical indexes, immune responses, intestinal mucosal morphology, and cecal microbial community structure were evaluated. The ABP group had greatest body weight (BW), average daily body weight gain (ADG), and intestinal villus height compared to other treatments (p < 0.05). The CABP group had a higher villus height/crypt depth ratio (V/C) compared with other treatments (p < 0.05). The expression levels of NF-κB were lower in the ABP group. The CNG group had higher Escherichia coli and Enterococcus contents in cecal samples compared to other treatments (p < 0.05). Serum glucose, uric acid, TNF-α, and Secretory Immunoglobulin A (S-IgA) levels were higher in broilers challenged with E. coli (p < 0.001) than that with saline. Broilers challenged with E. coli had reduced taxa richness in the cecal samples. Sequencing of 16S rRNA genes in cecal samples revealed that a lower proportion of Firmicutes and a higher proportion of Proteobacteria were detected in the broilers challenged with E. coli. Compared with the controls, dietary ABPS supplementation increased serum total protein, albumin, and S-IgA levels, but decreased serum glucose, uric acid, and TNF-α levels in broilers (p < 0.05). Diet supplemented with ABPS increased the Firmicutes/Bacteroidetes ratio and the abundance of Ruminococcaceae and Lachnospiraceae, and altered cecal microbiota community structure. These results suggest that ABPS can promote growth performance and improve intestinal morphology and microbiota community structure in broilers challenged with E. coli K88.

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Section: Introductionmentioning

confidence: 99%

Effects of Achyranthes bidentata Polysaccharides on Intestinal Morphology, Immune Response, and Gut Microbiome in Yellow Broiler Chickens Challenged with Escherichia coli K88

Liu

Wang

et al. 2018

Polymers

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“…Further, an increase in the villus height and villus height to crypt depth ratio are directly correlated with increased epithelial cell turnover (Fan et al, 1997) and an indicator of activated intestinal villi function (Langhout et al, 1999;Shamoto and Yamauchi, 2000) and it also stimulates intestinal blood flow. In addition, butyrate of stimulates cell growth and differentiation of normal cells and apoptosis (early cell death) of tumour cells which represents'butyrate paradox' (Canani et al, 2011).Previous studies showed increased jejunum villi height (Adil et al, 2010;Jerzsele et al, 2012;Chamba et al, 2014), villi height to crypt depth ratio (Hu and Guo, 2007;Shahir et al, 2013) and comparable crypt depth (Hu and Guo, 2007;Adil et al, 2010;Smulikowska et al, 2009;Chamba et al, 2014;Sayrafi et al, 2011;Antongiovanni et al, 2007) by supplementation of different forms of butyric acid. Lakshmi and Sunder (2015) 0.25 Liver weight + Aghazadeh and Yazdi (2012) It is clear from the Table 4 that inclusion of BA in broiler diet improves the weight of carcass indicating anabolic effect in broiler chicken.…”

Section: Antioxidant Effectmentioning

confidence: 99%

“…February 2018 | Volume 6 | Issue 2 | Page 64 Chamba et al (2014) cell death. The in vitro study of microbial count influenced due to organic acid is presented in Table 1.…”

Section: Advances In Animal and Veterinary Sciencesmentioning

confidence: 99%

Butyric Acid as an Antibiotic Substitute for Broiler Chicken A Review

Deepa¹,

Purushothaman²,

Vasanthakumar³

et al. 2018

Adv. Anim. Vet. Sci.

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“…Os efeitos benéficos da utilização do BS observados, tanto na interação com a FCO, como isoladamente nas fases de 1 a 7 e 1 a 42 dias, demonstram que esse ácido orgânico pode melhorar o desempenho de frangos de corte. Várias pesquisas corroboram com os resultados obtidos, evidenciando melhoras no desempenho de frangos de corte com a utilização de BS (LEVY et al, 2015;CHAMBA et al, 2014;DOLAN et al, 2016). Os benefícios obtidos com a utilização de BS podem ser atribuídos a ação antimicrobiana sobre bactérias patogênicas como Clostridium spp, Escherichia coli e Sallmonella spp (VAN DER WIELEN et al, 2000).…”

Section: Discussionunclassified

“…Os benefícios obtidos com a utilização de BS podem ser atribuídos a ação antimicrobiana sobre bactérias patogênicas como Clostridium spp, Escherichia coli e Sallmonella spp (VAN DER WIELEN et al, 2000). As propriedades antimicrobianas do ácido butírico reduzem a colonização entérica por microrganismos patogênicos, equilibrando as substâncias no trato gastrintestinal (FERNÁNDEZ RUBIO et al, 2009), além de efeitos benéficos sobre a mucosa intestinal (CHAMBA et al, 2014).…”

Section: Discussionunclassified

Farinha De Carne E Ossos E Butirato De Sódio Sobre O Desempenho Semanal De Frangos De Corte

Silva¹,

Santos²,

Scatolin³

et al. 2017

Colloq Agrariae

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RESUMO O objetivo desse trabalho foi avaliar a substituição parcial do farelo de soja por farinha de carne e ossos (FCO) e da suplementação com butirato de sódio (BS) sobre o desempenho de frangos de corte. Foram utilizados 140 pintos distribuídos em DIC em fatorial 2x2 (ausência e presença de BS x ausência e presença de FCO) com 5 repetições. O desempenho foi avaliado semanalmente por meio do consumo de ração (CR), ganho de peso (GP), conversão alimentar (CA) e viabilidade criatória (VC). De 1 a 14 dias e a utilização de FCO reduziu o CR e o GP, entretanto a inclusão de BS reverteu esses resultados. A inclusão de BS aumentou o CR e o GP de 1 a 7 e 1 a 42 dias. Concluiu-se que tanto a substituição do farelo de soja por FCO como a suplementação com BS são alternativas viáveis na alimentação de frangos de corte. Palavras-chave: ácidos orgânicos; consumo de ração; conversão alimentar; farinhas de origem animal; ganho de peso.

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Effect of Partially Protected Sodium Butyrate on Performance, Digestive Organs, Intestinal Villi and E. coli Development in Broilers Chickens

Cited by 68 publications

References 18 publications

Effects of Achyranthes bidentata Polysaccharides on Intestinal Morphology, Immune Response, and Gut Microbiome in Yellow Broiler Chickens Challenged with Escherichia coli K88

Effects of Achyranthes bidentata Polysaccharides on Intestinal Morphology, Immune Response, and Gut Microbiome in Yellow Broiler Chickens Challenged with Escherichia coli K88

Butyric Acid as an Antibiotic Substitute for Broiler Chicken A Review

Farinha De Carne E Ossos E Butirato De Sódio Sobre O Desempenho Semanal De Frangos De Corte

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