Effect of pelvic radiotherapy for prostate cancer on bowel, bladder, and sexual function: The patient's perspective

Crook, John M.; Esche, B.; Futter, Norman G.

doi:10.1016/s0090-4295(99)80458-0

Cited by 149 publications

(61 citation statements)

References 15 publications

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“…However, these problems were of mild character, even in the RT group, because the highest reported problem (incontinence) only reached a mean value of 1.5 on a 0 to 10 scale. The relatively high percentage of our RT patients using pads (17%), compared with 2% reported by others, 26,27 may be because those patients adapted to their incontinence problem by using urinary pads; therefore, it would explain the low frequency of reported incontinence problem. A similar level of reported urinary problems also was found in an earlier study comparing PC patients and controls.…”

Section: Discussionmentioning

confidence: 54%

Quality of life and symptoms in a randomized trial of radiotherapy versus deferred treatment of localized prostate carcinoma

Fransson

Damber

Tomić

et al. 2001

Cancer

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Section: Discussionmentioning

confidence: 54%

Quality of life and symptoms in a randomized trial of radiotherapy versus deferred treatment of localized prostate carcinoma

Fransson

Damber

Tomić

et al. 2001

Cancer

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“…More than one-third of patients treated with a four-eld box (using a conventional collimator and a treatment dose of 70 Gy) (22) have reported urgent bowel movements. In addition, 20% (37:189) and 7% (17:189) of patients who received the same treatment with a dose of 66 Gy reported rectal urgency and faecal leakage (23).…”

Section: Discussionmentioning

confidence: 99%

Long-term Symptoms after External Beam Radiation Therapy for Prostate Cancer with Three or Four Fields

et al. 2002

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“…Rates of ED after radical prostatectomy have been reported in the literature ranging from 29 to 91%. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] The rates of ED after conventional radiation therapy range from 40 to 65%, [22][23][24][25][26][27] and the rates of ED after brachytherapy range from 16 to 50%. 28 The true etiology of ED after radiation therapy remains controversial.…”

Section: Introductionmentioning

confidence: 99%

An analysis of erectile function after intensity modulated radiation therapy for localized prostate carcinoma

Brown

Brooks

Albert

et al. 2006

Prostate Cancer Prostatic Dis

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Radiation therapy for prostate cancer can cause erectile dysfunction (ED). Intensity Modulated Radiation Therapy (IMRT) can reduce the amount of radiation to surrounding tissues associated with ED. We characterize the incidence of and factors associated with ED in prostate cancer patients after IMRT at the National Naval Medical Center (NNMC). Patients potent by definition of the Sexual Health Inventory for Men (SHIM) before treatment completed the specific erectile questions of the SHIM after IMRT. Statistical analyses were performed to examine the relationships between several factors and ED. Thirty-two of 45 patients with mean age of 68.2 years (50-86 years) completed the SHIM. The median follow-up was 36.8 months (16-63.6 months) as defined by the time from completion of therapy to reassessment with the SHIM. Eight of 32 patients (25%) had no post-treatment ED (SHIM score 22-25), three of 32 (9%) had mild post-treatment ED (SHIM score 17-21), five of 32 (16%) had mild to moderate ED (SHIM score 12-16), five of 32 (16%) had moderate ED (SHIM score 8-11) and 11 of 32 (34%) had severe post-treatment ED (SHIM scoreo8). Posttreatment potency was significantly associated with the pre-treatment SHIM score (P ¼ 0.001) and history of hypertension (P ¼ 0.03). The mean radiation dose to the penile bulb and volume of penile bulb treated were not associated with post-treatment potency (P ¼ 0.38, 0.76, respectively). IMRT maintains potency in the majority of patients. This analysis compares favorably in preserving erectile function to previously reported series using conventional external beam radiation therapy techniques. The dose of radiation received by the penile bulb and volume of penile bulb were not associated with post-treatment ED in this analysis.

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Effect of pelvic radiotherapy for prostate cancer on bowel, bladder, and sexual function: The patient's perspective

Cited by 149 publications

References 15 publications

Quality of life and symptoms in a randomized trial of radiotherapy versus deferred treatment of localized prostate carcinoma

Quality of life and symptoms in a randomized trial of radiotherapy versus deferred treatment of localized prostate carcinoma

Long-term Symptoms after External Beam Radiation Therapy for Prostate Cancer with Three or Four Fields

An analysis of erectile function after intensity modulated radiation therapy for localized prostate carcinoma

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