Effect of percutaneous mitral balloon valvuloplasty on left atrial appendage function: Transesophageal echo study

Reddy, V. Ganeswara; Rajasekhar, D.; Vanajakshamma, V.

doi:10.1016/j.ihj.2012.07.008

Cited by 12 publications

(13 citation statements)

References 27 publications

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“…Thus, SEC can appear in the LA and subsequently increase LA clot formation and embolic phenomenon. 26 In our study, we observed SEC in 8 SR patients and 13 AF patients, which completely disappeared in 5 and 4 patients, respectively. Bernstein NE et al 27 reported SEC in 21 of 47 patients (45%) with MS in SR, and Karakaya et al 18 found that SEC completely disappeared in 7 of 20 patients with MS in SR after PTMC.…”

Section: Discussionsupporting

confidence: 57%

The Effects of Percutaneous Mitral Balloon Valvuloplasty on the Left Atrial Appendage Function in Patients With Sinus Rhythm and Atrial Fibrillation

Aslanabadi

Jafaripour

Toufan

et al. 2015

J Cardiovasc Thorac Res

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Introduction: Mitral stenosis (MS) causes structural and functional abnormalities of the left atrium (LA) and left atrial appendage (LAA), and studies show that LAA performance improves within a short time after percutaneous transvenous mitral commissurotomy (PTMC). This study aimed to investigate the effects of PTMC on left atrial function by transesophageal echocardiography (TEE). Methods: We enrolled 56 patients with severe mitral stenosis (valve area less than 1.5 CM2). All participants underwent mitral valvuloplasty; they also underwent transesophageal echocardiography before and at least one month after PTMC. Results: Underlying heart rhythm was sinus rhythm (SR) in 28 patients and atrial fibrillation (AF) in remainder 28 cases. There was no significant change in the left ventricular ejection fraction (LVEF), left ventricular end diastolic dimension (LVEDD), or the left ventricular end systolic dimension (LVESD) before and after PTMC in both groups. However, both groups showed a significant decrease in the left atrial volume index (LAVI) following PTMC (P=0.032 in SR and P=0.015 in AF group). LAA ejection fraction (LAAEF) and the LAA emptying velocity (LAAEV) were improved significantly after PTMC in both groups with SR and AF (P<0.001 for both). Conclusion: Percutaneous transvenous mitral commissurotomy improves left atrial appendage function in patients with mitral stenosis irrespective of the underlying heart rhythm.

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Section: Discussionsupporting

confidence: 57%

The Effects of Percutaneous Mitral Balloon Valvuloplasty on the Left Atrial Appendage Function in Patients With Sinus Rhythm and Atrial Fibrillation

Aslanabadi

Jafaripour

Toufan

et al. 2015

J Cardiovasc Thorac Res

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“…This result was similar to the previous studies who found non significant improvement in LAAAC (%) immediately post PTMC. 8 , 9 , 11 , 13 , 14 But at 6 months F/U we found significant improvement in LAAAC (%). This might be due to chronic reduction in afterload after successful PTMC which led to gradual improvement in LAA contractile function and hence LAAAC (%).…”

Section: Discussionmentioning

confidence: 65%

“…This result was similar to the previous studies who found significant improvement in LAA DTI velocities after PTMC. 8 , 9 , 10 …”

Section: Discussionmentioning

confidence: 99%

Study of immediate and late effects of successful PTMC on left atrial appendage function in patients with severe rheumatic mitral stenosis IN SINUS rhythm

Ansari

Siddiqui²,

Barge

et al. 2020

Indian Heart Journal

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Introduction Since its introduction in 1984, Percutaneous Transvenous Mitral Commissurotomy (PTMC) has become established as a safe and effective treatment for rheumatic Mitral Stenosis (MS).( Ben Farhat et al., 1998) 1 Chronic pressure and volume overload imposed by MS causes left atrial (LA) and Left Atrial Appendage (LAA) dysfunction. Risk of cerebrovascular accident (CVA) is increased approximately 17-fold in patients of MS in Atrial Fibrillation (AF) and is present even in patients of MS in sinus rhythm (SR). This study was undertaken to evaluate the effect of PTMC on LAA function by Trans-esophageal echocardiography (TEE) Doppler and Doppler Tissue Imaging (DTI). Methods Total 70 cases were enrolled in this study. Patients with symptomatic severe MS (Mitral Valve Area <1.5cm2), in SR, who underwent a successful PTMC during the period from May 2016 to May 2019 were selected. All the patients underwent Clinical examination, ECG, detailed TTE and TEE before, immediately after (within 24 h) & after 6 months of PTMC. Results There was non significant improvement in Left Atrial appendage fractional area change {LAAAC (%)} immediately Post PTMC but there was significant improvement at 6 months Post PTMC. There was significant increase in LAA PW Doppler velocities (LAAEDE, LAALDE and LAAF velocity) immediately Post PTMC which got further improved significantly at 6 months of follow up. There was significant increase in LAA DTI velocities (E LAA , A LAA and S LAA velocity) immediately Post PTMC which got further improved significantly at 6 months of follow up. Conclusion PTMC improves left atrial appendage function in patients with mitral stenosis.

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“…study where they observed LA SEC in 21 (45%) of 47 patients. In previous studies, incidence of LA SEC was 17%–90.7%. Ganeswara Reddy et al .…”

Section: Discussionmentioning

confidence: 89%

Predictive Value of D‐Dimer Levels and Tissue Doppler Mitral Annular Systolic Velocity for Detection of Left Atrial Appendage Thrombus in Patients with Mitral Stenosis in Sinus Rhythm

et al. 2015

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Effect of percutaneous mitral balloon valvuloplasty on left atrial appendage function: Transesophageal echo study

Cited by 12 publications

References 27 publications

The Effects of Percutaneous Mitral Balloon Valvuloplasty on the Left Atrial Appendage Function in Patients With Sinus Rhythm and Atrial Fibrillation

The Effects of Percutaneous Mitral Balloon Valvuloplasty on the Left Atrial Appendage Function in Patients With Sinus Rhythm and Atrial Fibrillation

Study of immediate and late effects of successful PTMC on left atrial appendage function in patients with severe rheumatic mitral stenosis IN SINUS rhythm

Predictive Value of D‐Dimer Levels and Tissue Doppler Mitral Annular Systolic Velocity for Detection of Left Atrial Appendage Thrombus in Patients with Mitral Stenosis in Sinus Rhythm

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