2015
DOI: 10.1016/j.ajic.2015.04.188
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Effect of perioperative mupirocin and antiseptic body wash on infection rate and causative pathogens in patients undergoing cardiac surgery

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Cited by 26 publications
(40 citation statements)
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“…10 Interestingly, a recent prospective study involving cardiac surgery patients found a similar reduction in superficial (but not deep or organ space) SSI rates irrespective of whether a regimen of chlorhexidine body wash and mupirocin nasal ointment was initiated before or after surgery. 8 This finding supports the potential role of postoperative contamination of surgical wounds in the causation of superficial SSIs. 10 In this regard, it might have been helpful for Durkin et al to have reported superficial and deeper space SSI rates separately to determine whether seasonal variation affected these SSIs equally.…”
Section: Seasonal Variation Of Surgical Site Infections: Why Does It supporting
confidence: 75%
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“…10 Interestingly, a recent prospective study involving cardiac surgery patients found a similar reduction in superficial (but not deep or organ space) SSI rates irrespective of whether a regimen of chlorhexidine body wash and mupirocin nasal ointment was initiated before or after surgery. 8 This finding supports the potential role of postoperative contamination of surgical wounds in the causation of superficial SSIs. 10 In this regard, it might have been helpful for Durkin et al to have reported superficial and deeper space SSI rates separately to determine whether seasonal variation affected these SSIs equally.…”
Section: Seasonal Variation Of Surgical Site Infections: Why Does It supporting
confidence: 75%
“…To this end, it would have been helpful for Durkin et al to have commented on the standard screening and/or decolonization practices for Staphylococcus aureus carriage, if any, as well as preoperative skin hygiene practices by patients such as routine antiseptic body wash within 24 h prior to surgery 7,8 at participating hospitals. Furthermore, it might have been helpful to report the number of patients who underwent "same-day" surgery (ie, were admitted to the hospital on the day of an elective surgery) vs those who had already been hospitalized for ≥1 day prior to their surgery.…”
Section: Seasonal Variation Of Surgical Site Infections: Why Does It mentioning
confidence: 99%
“…All studies contributed to the meta-analysis. [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] Nine of the eligible studies 19,22,24,25,[27][28][29][30]35 included cardiac patients and nine 20,21,23,26,[31][32][33]36,37 included orthopaedic patients; the remaining studies included both types of patients. Two cardiac studies were on paediatric populations 19,25 and the remaining were all adults.…”
Section: Observational Studiesmentioning
confidence: 99%
“…Mupirocin (2% ointment) was used under different regimens by 18 studies, 19,20,[22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37] and povidone-iodine was used in two studies as the nasal decolonization agent. 21,33 Chlorhexidine was used for skin decolonization in patients in the form of soaps for showering 19,20,[26][27][28][29]34,35,37 or wipes for skin cleansing. 21 Mouthwash using chlorhexidine was applied to patients in one study.…”
Section: Observational Studiesmentioning
confidence: 99%
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