“…Due to the shift of dissociation equilibria during heating and/or compression the results of inactivation experiments are prone to error if not designed correctly. Different authors showed that there is a strong pH dependence of spore inactivation during thermal treatment (Alderton, Ito, & Chen, 1976;Cameron, Leonard, & Barrett, 1980;Hutton, Koskinen, & Hanlin, 1991;Loewick & Anema, 1972;Sognefest, Hays, Wheaton, & Benjamin, 1948). The same dependence was observed during highpressure inactivation (Ardia, 2004;Wuytack, 1999;Wuytack & Michiels, 2001).…”