Effect of Pharmacological and Neurostimulation Interventions for Cognitive Domains in Patients with Bipolar Disorder: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Cognitive rehabilitation in bipolar spectrum disorder: A systematic review

“…Further research is needed to better understand the optimal parameters and mechanisms underlying the efficacy of CR in BD ( Tsapekos et al, 2022 ). The cognitive domains most commonly targeted in the included studies were verbal memory, attention, executive functions, and social cognition which is line with other studies ( King et al, 2019 , Chen et al, 2021 , Gillissie et al, 2022 ). These domains are known to be significantly impaired in bipolar patients and have a considerable impact on their daily functioning and overall well-being ( Bora et al, 2016 , Ehrminger et al, 2021 , Tsapekos et al, 2022 ).…”

Efficacy of Functional Remediation on Cognitive and Psychosocial Functioning in Patients with Bipolar Disorder: Study Protocol for a Randomized Controlled Study

“…Finally, if the results of the present study confirm the effectiveness of FR in BD, FR could be integrated into structured rehabilitation programs and combined with other nonpharmacological interventions targeting cognitive performance and aiming for functional improvement, such as physical exercise [82][83][84][85][86] or neurostimulation [85]. Establishing whether combined interventions provide greater or faster improvements, as has been observed in trials including participants diagnosed with schizophrenia [86][87][88], could provide valuable information for clinicians and mental health services.…”