Effect of photografting 2-hydroxyethyl acrylate on the hemocompatibility of electrospun poly(ethylene-co-vinyl alcohol) fibroporous mats

Sulfobetaine‐functionalized electrospun poly(ethylene‐co‐vinyl alcohol) membranes for blood filtration

“…However, the maximum DG obtained as a result of 60 min of UV irradiation was much lower than that obtained by Yang et al . This difference was ascribed to the poor availability of the monomer and initiator when they were locked in the fibers during electrospinning . Hence, our approach permitted the modification of membranes to improve the desired properties but to a limited extent.…”

“…Furthermore, the fiber diameter reached a maximum of 2.3 ± 0.3 μm after 60 min of UV irradiation (Figure ). The increased fiber diameter was ascribed to the formation of the SMDB‐grafted EVAL copolymer, mediated by the photoinitiator, as a result of UV irradiation …”

“…The previously established method of the in situ addition of the monomer SMDB and photoinitiator benzophenone (BP) was followed to prepare EVAL‐ g ‐PSMDB electrospun mats . A 9% w/v EVAL solution was prepared by the overnight dissolution of EVAL in a 70/30 2‐propanol–water mixture at 60–70 °C.…”

“…Modification not only rendered EVAL membranes hydrophilic but also enhanced their hemocompatibility. However, the modification did not significantly alter the white blood cell (WBC) adhesion by EVAL membranes …”

“…However, the modifications of electrospun EVAL membranes for the improvement of hemocompatibility have rarely been reported. In one of our previous studies, the effect of the grafting of 2‐hydroxyethyl acrylate (HEA) chains on EVAL was investigated . Modification not only rendered EVAL membranes hydrophilic but also enhanced their hemocompatibility.…”