Effect of physical training on QTc interval in elderly people

Schuit, Albertine J.; Dekker, Joost; Vegt, Femmie de; Verheij, Ton C; Rijneke, Rob D.; Schouten, Evert G.

doi:10.1016/s0022-0736(98)90041-3

Cited by 18 publications

(7 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…People who performed physical activity at least once a week had a 50% lower risk of developing a prolonged QTc compared with physically inactive people. Consistent with our study, regular physical activity favorably impacts on QTc interval duration in elderly people, particularly in women, probably through a more favorable autonomic balance due to increased parasympathetic activity (25).…”

Section: Results -supporting

confidence: 91%

Incidence and Risk Factors of Prolonged QTc Interval in Type 1 Diabetes

Giunti

Bruno²,

Lillaz³

et al. 2007

Diabetes Care

View full text Add to dashboard Cite

OBJECTIVE -Corrected QT (QTc) prolongation is predictive of cardiovascular mortality in both the general and diabetic populations. As part of the EURODIAB Prospective Complication Study, we have assessed the 7-year incidence and risk factors of prolonged QTc in people with type 1 diabetes. RESEARCH DESIGN AND METHODS-A total of 1,415 type 1 diabetic subjects, who had normal QTc at baseline, were reanalyzed after the 7-year follow-up period. QTc Ͼ0.44 s was considered abnormally prolonged.RESULTS -Cumulative incidence of prolonged QTc was 18.7%, which is twofold higher in women than in men (24.5 vs. 13.9%, P Ͻ 0.0001). At the baseline examination, incident cases were older and less physically active than nonincident cases, had higher mean values of systolic blood pressure and HDL cholesterol, and had higher frequencies of hypertension, coronary heart disease, and distal symmetrical polyneuropathy. In multivariate logistic regression analyses, female sex and higher values of A1C and systolic blood pressure were associated with the risk of prolonged QTc, whereas physical activity and BMI within the range of 21.5-23.2 kg/m 2 were protective factors. In women, association with modifiable factors, particularly BMI, was stronger than in men.CONCLUSIONS -In type 1 diabetic subjects from the EURODIAB cohort, female sex, A1C, and systolic blood pressure are predictive of prolonged QTc, whereas physical activity and BMI within the range of 21.5-23.2 kg/m 2 play a protective role. These findings are clinically relevant, as they may help to identify subjects at higher risk for prolonged QTc, as well as provide potential targets for risk-lowering strategies.

show abstract

Section: Results -supporting

confidence: 91%

Incidence and Risk Factors of Prolonged QTc Interval in Type 1 Diabetes

Giunti

Bruno²,

Lillaz³

et al. 2007

Diabetes Care

View full text Add to dashboard Cite

show abstract

“…Decreased HRV and increased heart rate before and during exercise in healthy people can increase cardiac sudden death (16). The findings of the present research are consistent with the results of some reasearches that show no change in the cardiac electrical waves after exercises (17)(18)(19). The obvious reaction to HR elevation is the slight shortening of QT intervals and QRS (20).…”

Section: Discussionsupporting

confidence: 91%

Interactive Effects of Aerobic Exercise and Music on Electrical Activity of the Heart in Non-Athletic Men

et al. 2019

View full text Add to dashboard Cite

Background:The effect of exercises on the heart has been widely studied. Music can stimulate emotions as well as changes in cardiac activity. Objectives: The present research aimed to investigate the effect of aerobic training and music on the electrical activity of the heart in non-athletic men. Methods: A total of 32 non-athletic men were selected and divided into four groups (n = 8) including; (1) aerobic exercises, (2) music without aerobic exercises, (3) aerobic exercise with music, and (4) control subjects. Groups 1 and 3 only performed aerobic exercises for eight weeks, groups 2 and 3 listened to music for eight weeks, and group 4 only had their daily activities during this period. At the beginning of the study and at the end of the eighth week, the subjects' electrocardiogram (ECG) was measured. To analyze the findings, paired sample t-test and two-way ANOVA were used at a significance level of 0.05. Results:Aerobic training had a significant effect on QRS wave increase (P ≤ 0.05). Music had a significant effect on heart rate (HR) reduction and QRS wave enhancement (P ≤ 0.05). Aerobic exercise along with music had significant interactive effects on HR reduction and QRS wave enhancement (P ≤ 0.05). However, aerobic training had no significant effect on HR (P ≥ 0.05). Aerobic exercise and music had a significant effect on PQ interval, QT interval, QTc, and P wave (P ≥ 0.05). Furthermore, aerobic exercise with music had no interactive effects on PQ interval, QT interval, QTc, and P wave (P ≥ 0.05). Conclusions:According to the results of the study, aerobic exercise with music can help improve some cardiac parameters of nonathletic men.

show abstract

“…Other studies used the Bazett formula for correction and found a decrease in QTc, but they did not report heart rate behavior after weight loss (20,21). Also in nonobese subjects physical training determines a shortening of QTc (22), but in this population the correction was done once again with the Bazett formula and heart rate was lower after training.…”

Section: Discussionmentioning

confidence: 99%

The Myth of QT Shortening by Weight Loss and Physical Training in Obese Subjects With Coronary Heart Disease

Gondoni

Titon

Montano

et al. 2011

Obesity

View full text Add to dashboard Cite

This study aims to describe the changes that a period of low‐calorie diet and physical training determines in heart rate and in corrected QT (QTc) interval in obese patients with coronary heart disease (CHD) and to verify whether it is effective in shortening the QT interval using three different methods for QT correction. Two hundred and seventy obese white patients (162 males—60%) affected with stable CHD and treated with β‐blockers were retrospectively studied in the setting of a program aimed at losing weight through training (aerobic activity + strength exercise) and diet (80% of estimated resting energy expenditure). Age was related to RR interval, QTc was related to left ventricular ejection fraction (EF) while sex exerted no effects. At the end of the study period heart rate decreased by 8.3% and noncorrected QT increased by 3.0%; QT corrected with the Bazett formula decreased by 0.7% (P = 0.007), QT corrected with the Fridericia formula increased by 0.5% (P = 0.023), whereas the modifications were nonsignificant when the Framingham correction was used. In conclusion, contrary to the current views, physical training and diet, which are effective in reducing heart rate, produced no clinically relevant change in the QT interval.

show abstract

Effect of physical training on QTc interval in elderly people

Cited by 18 publications

References 16 publications

Incidence and Risk Factors of Prolonged QTc Interval in Type 1 Diabetes

Incidence and Risk Factors of Prolonged QTc Interval in Type 1 Diabetes

Interactive Effects of Aerobic Exercise and Music on Electrical Activity of the Heart in Non-Athletic Men

The Myth of QT Shortening by Weight Loss and Physical Training in Obese Subjects With Coronary Heart Disease

Contact Info

Product

Resources

About