Effect of phytic acid on the setting times and tensile strengths of calcium silicate‐based cements

Uyanık, Özgür; Nagaş, Emre; Eren, Selen Küçükkaya; Çehrelį, Zafer C.; Vallittu, Pekka K.; Lassila, Lippo

doi:10.1111/aej.12314

Cited by 8 publications

(7 citation statements)

References 29 publications

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“…High water: powder ratio increases porosity and solubility of the cement, thus compromising the mechanical properties of the set material (Li et al, 1994), and this is also applicable to MTA and Biodentine ™ as a high water:powder ratio would adversely affect properties. The use of IP6 is thought to result in less water in the mixed cement; however, no improvement in the diametral tensile strength was detected (Uyanik et al, 2019).…”

Section: Potential Applications Of Ip6 In Dentistry Cementsmentioning

confidence: 98%

“…MTA exhibits a myriad of drawbacks such as a long setting time, poor handling characteristics and low washout resistance (Dawood et al, 2017). At a certain concentration, IP6 can effectively decrease the setting time of calcium silicate-based cements without altering their diametral tensile strength, and this effect was more pronounced with Biodentine ™ compared with MTA (Uyanik et al, 2019). Acceleration of the setting time could be through the hydrophilic nature of IP6 having a synergistic effect with calcium silicate-based cements, which sets through a hydration reaction.…”

Section: Potential Applications Of Ip6 In Dentistry Cementsmentioning

confidence: 99%

“…Although the scholarly interest in IP6 furnished a number of intriguing findings regarding its application in dentistry, this interest reached a hiatus. Recently, interest in IP6 has been revitalized with several research papers exploring potential dental applications including its use in dentifrices and cements, and other new applications such as etchant in adhesive dentistry, chelating agent in endodontics or anti-staining agent added to dentifrices (Nassar et al, 2013;Nassar et al, 2015;Milleman et al, 2018;Parkinson et al, 2018;Uyanik et al, 2019). In 1983, Ernst Graf was highly active in researching different features of IP6 and its potential in a vast array of applications.…”

Section: Introductionmentioning

confidence: 99%

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Phytic Acid: Properties and Potential Applications in Dentistry

Nassar

Maki

et al. 2021

Front. Mater.

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Inositol hexaphosphate (IP6) is the most abundant inositol phosphate in nature and an essential molecule for different biological functions. IP6 has a unique structure granting it distinctive properties; a high negative charge density provides IP6 with an immense chelating ability and valuable antioxidant properties. IP6 is also simple and cost-effective to produce. These features have attracted researchers and entrepreneurs to further study IP6 for a wide variety of applications in areas such as pharmaceutical, food and chemical industries, medicine, pharmacy, nutrition, and dentistry. The interest in IP6 in the dental field unfolded many decades ago following identification of a cariostatic ability and a positive impact on reducing enamel dissolution. Subsequently, IP6’s anti-plaque, anti-calculus and cement-forming properties have been investigated. Despite encouraging findings, there was a phase of decreased attention to IP6 which slowed down research progress. However, the potential use of IP6 has recently been revisited through several publications that provided deeper understanding into its mechanisms of action in the aforementioned applications. Studies have also explored new applications in endodontics, adhesive, preventive and regenerative dentistry, and IP6’s role in improving the characteristics and performance of dental materials. Evidence of the merits of IP6 in dentistry is now substantial, and this narrative review presents and discusses the different applications proposed in the literature and gives insights of future use of IP6 in the fields of orthodontics, implant and pediatric dentistry.

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Section: Potential Applications Of Ip6 In Dentistry Cementsmentioning

confidence: 98%

Section: Potential Applications Of Ip6 In Dentistry Cementsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Phytic Acid: Properties and Potential Applications in Dentistry

Nassar

Maki

et al. 2021

Front. Mater.

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“…10 IP6'nın mikrosertlik ve bağlanma dayanımı üzerine etkisi, şelasyon kabiliyeti, pulpa kök hücrelerine ve kalsiyum silikat esaslı siman türlerine olan etkisi, antimikrobiyal etkinliği ve rejeneratif endodontideki rolü araştırılmıştır. [12][13][14][15][16][17][18] Ancak %1 IP6'nın, KH'yi uzaklaştırma kabiliyeti ile ilgili literatürde yalnızca bir çalışma bulunmaktadır. 19 Bu çalışmanın amacı, KH'nin kök kanallarından uzaklaştırılmasında, IP6 ve EDTA solüsyonlarının yalnız başına ve NaOCl ile birlikte kullanıldığında etkinliğini değerlendirmektir.…”

Section: Abstract Objectiveunclassified

Efficacy of Phytic Acid as an Endodontic Chelator on Removing Calcium Hydroxide from Root Canals: An In Vitro Study

FALAKALOĞLU¹,

ŞEN²,

ÖZATA³

et al. 2022

Turkiye Klinikleri J Dental Sci

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“…On the basis of these advantages, 1% IP6 was proposed as an alternative chelating agent in a recent report (11). Variables such as its effect on microhardness (16), removal ability of intracanal medication (17), effect on dentine bond (18), chelating efficacy (19), calcium loss from root dentine (20), effect on dental pulp stem cells (21), effect on calcium silicate based cements (22), antimicrobial effect (23) and role in regenerative endodontics (24) have been reported previously.…”

Section: Preparation Of 1% Ip6mentioning

confidence: 99%

Erosive potential of 1% Phytic Acid on radicular dentine at different time intervals

et al. 2019

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The objective of this in-vitro study was to compare the erosive potential and smear layer removal ability of 1% Phytic acid (IP6) and 17% Ethylenediaminetetaacetic acid (EDTA). Methods: Canal preparation of 225 single rooted extracted human teeth was performed with Protaper NiTi rotary instruments. Teeth were divided into three groups according to the final irrigation protocol. Group 1: Saline irrigation (n=75), Group 2: 17% EDTA (n=75), Group 3: 1% Phytic Acid (n=75). Roots were splitted and observed under Scanning Electron Microscope (SEM) for erosion and smear layer removal. Mean differences between the groups for smear layer removal and erosion were assessed using the Kruskal Wallis and Mann Whitney U test. (P≤0.05) Friedman and Willcoxon Signed Rank tests were used to make comparisons within the groups. Results: Group 3 was significantly less erosive than Group 2 at all root portions (P<0.001). With regards to smear layer removal, group 2 (EDTA) removed more smear layer compared to group 3 (Phytic acid) at all root portions (P<0.001). Both 17% EDTA and 1% IP6 removed significantly less smear layer in the apical root portion. Intra group comparisons revealed no significant differences at any root level. There was a time dependent increase in erosion and smear layer removal in Group 2, with severe erosion at 5 minutes time interval. In Group 3, however, there was moderate erosion and smear removal at 3 and 5 minutes interval. Conclusion: IP6 at the concentration of 1% and pH 3 was less erosive than 17% EDTA. It exhibited moderate smear layer removal ability.

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Effect of phytic acid on the setting times and tensile strengths of calcium silicate‐based cements

Cited by 8 publications

References 29 publications

Phytic Acid: Properties and Potential Applications in Dentistry

Phytic Acid: Properties and Potential Applications in Dentistry

Efficacy of Phytic Acid as an Endodontic Chelator on Removing Calcium Hydroxide from Root Canals: An In Vitro Study

Erosive potential of 1% Phytic Acid on radicular dentine at different time intervals

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