Effect of polymorphisms at the ghrelin gene locus on carcass, microstructure and physicochemical properties of longissimus lumborum muscle of Polish Landrace pigs

Allele frequency for c.335 A>C polymorphisms in porcine ghrelin/obestatin prepropeptide gene and association analysis with performance traits in various pig breeds

“…The AA homozygous had higher average EMA than the AC heterozygous in Duroc gilts (P = 0.014). Wojtysiak and Kaczor (2011) also detected an association between this SNP and EMA; however, the genotypic effect was different because they indicated that the AC heterozygous animals had the largest average EMA. Moreover, we could not detect any associations between this SNP and EMA in Landrace, Large White, or LWD populations (Table 2).…”

“…Kim et al (2004) reported that the AA homozygous pigs had higher IMF marbling score than the CC homozygous in a Berkshire population. However, Wojtysiak and Kaczor (2011) reported that there was no association between IMF and c.335 A>C in Polish Landrace. A possible cause of these opposing results is that the GHRL c.335 A>C polymorphism itself may have insignificant impact on fat accumulation but may have weak-tomoderate linkages with IMF and BFT QTLs that differ among breeds and populations.…”

“…Although the CC homozygous had a tendency toward higher ADG and BFT than the AA homozygous in Landrace gilt (P = 0.071 and P = 0.080, respectively), we could not detect statistically significant difference in ADG and BFT between any different genotype pairs within the four populations examined. On the other hand, noticeable genotypic effects of c.335 A>C on BFT have been reported in Berkshire, Polis Landrace, and Italian Large White breeds (Kim et al 2004;Wojtysiak and Kaczor 2011;Fontanesi et al 2012). However, the reported genotypic effects of c.335 A>C on BFT greatly varied among studies.…”

“…However, the reported genotypic effects of c.335 A>C on BFT greatly varied among studies. Kim et al (2004) reported that the AC heterozygous had the highest average BFT, whereas Wojtysiak and Kaczor (2011) reported that the AC heterozygous had the lowest average BFT. Furthermore, we could not detect significant association between IMF and c.335 A>C in Duroc and LWD pigs, although pigs with the AC genotype showed a trend to have higher IMF than the AA homozygous in Duroc (P = 0.064 in gilt, P = 0.072 in boar).…”

“…Thus, the GHRL c.335 A>C polymorphism has been thought to be a potential candidate gene for the QTLs affecting IMF, BFT, or both on SSC13. Recently, the effect of this polymorphism was investigated in Polis Landrace pigs (Wojtysiak and Kaczor 2011). However, the detected effects of this GHRL polymorphism on porcine economic traits greatly varied between the two reports.…”