Effect of Posterior Subtenon Triamcinolone Injection during Vitrectomy for Idiopathic Epiretinal Membrane

Kim, Sung Il; Park, Sung Who; Byon, Ik Soo; Lee, Ji Eun

doi:10.3341/jkos.2015.56.8.1236

Cited by 2 publications

(3 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, we found that CMT can decrease significantly after vitrectomy with or without adjuvant intravitreal corticosteroid injection for ERM. In a previous study by Kim et al [24], the CMT was rapidly reduced during the first 3 months after ERM surgery, and this reduction was persistent after 12 postoperative months. However, it rarely reached a normal value.…”

Section: Discussionmentioning

confidence: 85%

“…The authors explained that the result might be related to the low prednisolone dosage used (100 mg/day for 5 days). Kim et al [24] evaluated the effects of postoperative subtenon triamcinolone injections (40 mg/1 mL) in eyes with ERM after vitrectomy and found no beneficial effects compared with the control. The efficacy of combined oral or subtenon corticosteroid injection and vitrectomy seems too low to achieve a significant difference in macula edema resolution compared with that of vitrectomy alone.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy of Combined Vitrectomy with Intravitreal Corticosteroid Injection for Idiopathic Epiretinal Membrane Removal on Anatomical and Functional Outcomes: A Meta-Analysis

2022

View full text Add to dashboard Cite

Background: Macular edema can be a cause of visual loss in eyes undergoing vitrectomy with epiretinal membrane(ERM) peeling. Objective: To evaluate the efficacy of combined vitrectomy with intravitreal corticosteroid injection for ERM. Methods: We conducted a systematic literature review by searching PubMed, Embase, and Medline up to December 2020 for studies that evaluated the effect of intravitreal corticosteroid injection during vitrectomy for ERM. Follow-up data on postoperative best-corrected visual acuity (BCVA) and central macular thickness (CMT) were collected and pooled using the standard mean deviation (SMD) with the corresponding 95% confidence interval (CI). Heterogeneity was statistically quantified using I2 statistics, and a meta-analysis was performed using a random-effects model. Results: Eight studies provided data on a total sample of 443 eyes. The meta-analysis revealed that concomitant intravitreal corticosteroid administration during vitrectomy contributed to a significant reduction in CMT than vitrectomy alone at 3 months after operation (pooled SMD = −0.353; 95% CI, −0.594 to −0.111; p = 0.004). However, between the two groups, no significant difference was found in CMT reduction at 1 and 6 months after operation and in postoperative BCVA improvement at 1, 3, and 6 months after operation. Conclusion: Combined treatment with vitrectomy and intravitreal corticosteroid injection may accelerate CMT reduction 3 months after ERM surgery. However, it did not result in a significant change in CMT and BCVA compared with vitrectomy alone at the end of follow-up.

show abstract

Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Efficacy of Combined Vitrectomy with Intravitreal Corticosteroid Injection for Idiopathic Epiretinal Membrane Removal on Anatomical and Functional Outcomes: A Meta-Analysis

2022

View full text Add to dashboard Cite

show abstract

“…TA is a steroid with anti-inflammatory properties, and it may affect the development of postoperative IRF. However, in our previous study, postoperative outcomes of ERM surgery were compared between two groups classified according to intravitreal or posterior subtenon TA injection at the end of the operation [17,18]. No significant differences were found in terms of visual acuity and foveal thickness.…”

Section: Discussionmentioning

confidence: 96%

Perioperative intraretinal fluid observed using optical coherence tomography in the epiretinal membrane

Lee

Kwon

et al. 2020

BMC Ophthalmol

Self Cite

View full text Add to dashboard Cite

Background: Postoperative intraretinal fluid (IRF) is reportedly associated with visual outcomes after epiretinal membrane (ERM) surgery. However, preoperative IRF is common, and persistent IRF would have different impact on visual function from postoperative newly developed IRF. Therefore, we aimed to investigate the incidence rate and clinical implications of perioperative IRF in ERM. Methods: Medical records of patients who underwent vitrectomy for idiopathic ERM between January 2014 and January 2017 were reviewed retrospectively. The incidence of IRF was analyzed using optical coherence tomography preoperatively and 1, 3, and 6 months postoperatively. On the basis of the presence or absence and the time of detection of IRF, patients were divided into three groups, namely preoperative IRF group, New IRF group, and IRF(−) group. Correlations of various parameters including age, sex, baseline visual acuity (VA), central subfield macular thickness, lens status, and surgical factors with IRF, along with the effect of IRF on VA, were evaluated. Results: This study included 155 eyes from 155 patients. Thirty-six (23.2%) and 49 (31.6%) eyes demonstrated preoperative and newly developed IRF, respectively. Seventy eyes (45.2%), which did not exhibit IRF during the study period, were assigned to the IRF(−) group. At baseline, the IRF(−) group showed a better VA than the other two groups. Postoperatively, VA improved significantly in all three groups. There was no difference in VA between the IRF(−) and new IRF groups at 6 months; however, the preoperative IRF group had significantly lower VA than the other two groups. Conclusion: IRF associated with ERM was frequently observed preoperatively and postoperatively, but it did not prevent postoperative vision improvement. Preoperative IRF was related to lower postoperative vision improvement.

show abstract

Effect of Posterior Subtenon Triamcinolone Injection during Vitrectomy for Idiopathic Epiretinal Membrane

Cited by 2 publications

References 33 publications

Efficacy of Combined Vitrectomy with Intravitreal Corticosteroid Injection for Idiopathic Epiretinal Membrane Removal on Anatomical and Functional Outcomes: A Meta-Analysis

Efficacy of Combined Vitrectomy with Intravitreal Corticosteroid Injection for Idiopathic Epiretinal Membrane Removal on Anatomical and Functional Outcomes: A Meta-Analysis

Perioperative intraretinal fluid observed using optical coherence tomography in the epiretinal membrane

Contact Info

Product

Resources

About