Effect of precocene II on the endocrine regulation of development and reproduction in the bug, Oncopeltus fasciatus

Masner, P.; Bowers, William S.; Kälin, Maria; Mühle, T.

doi:10.1016/0016-6480(79)90103-5

Cited by 66 publications

(21 citation statements)

References 7 publications

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“…When the larvae of O. fasciatus were exposed to an extract of the common ornamental bedding plant Ageratum houstonianum, they metamorphosed prematurely into miniature adults with small wings. [101][102][103] Bowers identified these compounds and named them as precocenes I and II (Fig. 4).…”

Section: Discovery Of Precocenesmentioning

confidence: 99%

Insect juvenile hormone action as a potential target of pest management

Minakuchi

Riddiford

2006

J. Pestic. Sci.

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Juvenile hormone (JH) is a sesquiterpenoid hormone that regulates growth and development in insects. Since JH is a hormone specific to insects and other arthropods, compounds disrupting JH action in insects are expected to be ideal insecticides with low toxicity to non-target organisms. Many natural or synthetic analogs with JH-like or anti-JH activity have been identified, and some potent JH mimics have been used as insecticides. Recent studies on the enzymes in JH biosynthetic and metabolic pathways should be helpful for the discovery of more potent analogs and for the establishment of new means of pest management using recombinant DNA technology. © Pesticide Science Society of Japan Keywords: juvenile hormone (JH), insect metamorphosis, insect growth regulators, biosynthesis and metabolism of JH. Review* To whom correspondence should be addressed. E-mail: chieka_minakuchi@yahoo.com © Pesticide Science Society of Japan doptera. 17,18) Higher Diptera such as D. melanogaster and the blowfly Calliphora vomitoria produce JH III bisepoxide. 19,20) A small amount of methyl farnesoate, a precursor of JH III, was found in cockroach embryos and larvae. [20][21][22] Methyl farnesoate has also been identified in crustaceans 23) and is thought to have a JH-like action in female reproduction. 24)12Ј-OH JH III identified from the corpora allata of the African locust Locusta migratoria migratorioides was reported to exhibit JH activity when a high dose of this compound was topically applied to Tenebrio pupae. 25,26) Biosynthesis, Transport and Metabolism of Juvenile HormoneIn insects, JH is synthesized in the corpora allata via the mevalonate pathway (Fig. 2).27) The mevalonate pathway also exists in mammals and plants, and the early steps from acetylCoA to farnesyl diphosphate are conserved among these organisms. Importantly, insects and other arthropods do not synthesize cholesterol de novo but have to acquire it from dietary sources because they lack the genes encoding squalene synthase and other subsequent enzymes of the sterol branch. 28,29) Another peculiarity of the mevalonate pathway in insects is the capacity to synthesize JH via the isoprenoid branch.The genes encoding the enzymes in the mevalonate pathway from acetyl-CoA to farnesyl diphosphate have been identified in the genome of D. melanogaster and the malaria mosquito Anopheles gambiae, and in an EST library of the pine engraver Ips pini.27) However, it has been difficult to identify the genes encoding enzymes from farnesyl diphosphate to JH

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Section: Discovery Of Precocenesmentioning

confidence: 99%

Insect juvenile hormone action as a potential target of pest management

Minakuchi

Riddiford

2006

J. Pestic. Sci.

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“…In these non-social insect species, precocenes also affect several aspects of behavior such as aggression (Chen et al, 2005a), mating behavior (Walker, 1978), flight behavior (Rankin, 1980), maternal defensive behavior (Kight, 1998) and sexual behavior (Pathak and Bhandari, 2002;Ringo et al, 2005). In most cases the physiological, but not all the behavioral effects, were reversible by JH replacement therapy (Walker, 1978;Masner et al, 1979;Unnithan and Nair, 1979;Rankin, 1980;Li et al, 1993;Kight, 1998;Pathak and Bhandari, 2002;Chen et al, 2005a). However, despite the plethora of species tested and abundant studies that were conducted using precocenes, only few have directly tested the change in JH titer post treatment (Pratt and Bowers, 1977;Sohn et al, 1991;Chen et al, 2005a).…”

Section: Introductionmentioning

confidence: 99%

Precocene-I inhibits juvenile hormone biosynthesis, ovarian activation, aggression and alters sterility signal production in bumble bee (Bombus terrestris) workers

Amsalem

Teal

Grozinger

et al. 2014

Journal of Experimental Biology

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Juvenile hormone (JH) is an important regulator of development and physiology in insects. While in many insect species, including bumble bees, JH functions as gonadotropin in adults, in some highly eusocial insects its role has shifted to regulate social behavior including division of labor, dominance and aggression. Studying JH functions across social insect species is important for understanding the evolution of sociality; however, these studies have been limited because of the inability to reduce JH levels without surgically removing its glandular source, the corpora allata. Precocene is known to inhibit JH biosynthesis in several non-social insects, but has been poorly studied in social insects. Here, we tested whether precocene-I can effectively reduce JH levels in Bombus terrestris workers, and examined its effects on their physiology and behavior. Precocene-I treatment of three-worker groups decreased JH titer and ovarian activation, irrespective of the bees' dominance rank within the group, and was remedied by JH replacement therapy. Precocene-I also decreased aggressiveness and increased ester-sterility signal production; these changes were rank-dependent, and affected mainly the most reproductive and the least aggressive workers, respectively, and could not be remedied by JH replacement therapy. These results clearly confirm the role of JH as a gonadotropin and mediator of aggression in B. terrestris, and indicate that JH effects are associated with worker dominance rank. The ability to chemically reduce JH titer provides us with a non-intrusive method to probe the evolutionary changes associated with JH and the hormonal mechanisms that are associated with reproduction and behavior in social insects.

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Section: Introductionmentioning

confidence: 99%

“…In addition to inducing precocious development in immature stages, precocene has also been shown to produce sterilization effects in certain female insects (Bowers 1976;Bowers et al 1976;Bowers and Martinez-Pardo 1977;Masner et al 1979;Belles and Messeguer 1981;Farag and Varjas 1981;Martinez Carrau et al 1981;Zamorano et al 1981;Samaranayaka-Ramasamy and Chaudhury 1982;Wilson et al 1983;Bitsch and Bitsch 1984;Belles et al 1985). Unfortunately precocene is without effect against most holometabola and is active only on very few sensitive genera of Heteroptera and Acrididae (Masner et al 1979;Pener et al 1981;Pratt et al 1981;Alrubeai 1986). In susceptible insect species, precocenes act as anti-allatins or allatocidal agents causing atrophy and necrosis of the corpora allata (Bowers and Martinez-Pardo 1977;Pener et a11978;Schooneveld 1979a;Feyereisen et al 1981;Soderlund et al 1980;Pratt et al 1980;Miall and Mordue 1980;Hales and Mittler 1981;Bowers and Feldlaufer 1982;Pratt 1983;Pratt and Pener 1983;Lange et al 1983;Raynaud et al 1985).…”

Section: Introductionmentioning

confidence: 99%

Influence of precocene-I on the development of vitellogenic oocytes inTrogoderma granarium Everts (Coleoptera: Dermestidae)

Chellayan

Karnavar

1988

Proc. Indian Acad. Sci. (Anim. Sci.)

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Female Troqoderma granarium pupae, 0-96 h old, were treated with precocene-I at 6 h intervals. Reduction in the vitellogenic oocyte number was observed in adults after precocenetreatment at specific ages. Precocene-I was effective when applied to 6, 18,30,42, 54 and 90 h old pupae while in 0, 12, 24, 36, 48, 60, 66, 72, 78,84 and 96 h old pupae this compound was not significantly effective. Corpus allatum activity is a major contributory factor towards precocene susceptibility. The results suggest that pupae at different ages exhibit periodic changes in corpus allatum activity that might be related to cycles of development in the reproductive system.

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Effect of precocene II on the endocrine regulation of development and reproduction in the bug, Oncopeltus fasciatus

Cited by 66 publications

References 7 publications

Insect juvenile hormone action as a potential target of pest management

Insect juvenile hormone action as a potential target of pest management

Precocene-I inhibits juvenile hormone biosynthesis, ovarian activation, aggression and alters sterility signal production in bumble bee (Bombus terrestris) workers

Influence of precocene-I on the development of vitellogenic oocytes inTrogoderma granarium Everts (Coleoptera: Dermestidae)

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