Effect of prior thyroid cancer on survival of primary liver cancer: a study based on the SEER database

Liu, Hong; Heng, Xin; Tian, Yuan; Yang, Zhong-Jin

doi:10.1038/s41598-022-17729-4

Cited by 4 publications

(8 citation statements)

References 34 publications

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“…Although there was no statistical difference in median OS between the two groups, large-sample prospective studies are still needed to investigate the role of prior thyroid cancer in PC prognosis. A previous study has shown that prior thyroid cancer can reduce the incidence of dying from liver cancer only in female patients 10 . Interestingly, we found reduced PC-speci c mortality only in male PC patients with prior thyroid cancer.…”

Section: Association Between the History Of Thyroid Cancer And Pc-spe...mentioning

confidence: 98%

“…Prior thyroid cancer has been found in many studies as a favorable prognostic factor for second primary tumors 10,11 . Thyroid cancer is also bene cial for the survival of subsequent liver cancer 10 and breast cancer 11 . Nevertheless, research about the association between prior thyroid cancer and PC is rare, and further studies are required on these two cancers with very different prognoses.…”

Section: Introductionmentioning

confidence: 99%

“…For example, hypothyroidism is associated with autoimmune pancreatitis, a potential risk factor for PC 8,9 . Prior thyroid cancer has been found in many studies as a favorable prognostic factor for second primary tumors 10,11 . Thyroid cancer is also bene cial for the survival of subsequent liver cancer 10 and breast cancer 11 .…”

Section: Introductionmentioning

confidence: 99%

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Value of thyroid cancer history in the prognosis of pancreatic cancer: a SEER population-based study

Wang

Chen

et al. 2022

Preprint

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Thyroid cancer patients have a good prognosis, and their long survival increases the likelihood of developing a second primary tumor. Meanwhile, pancreatic cancer (PC) has a poor prognosis and therapeutic efficacy. However, the association between prior thyroid cancer and the subsequent PC prognosis is unknown. Herein, we selected pathologically diagnosed PC patients older than 17 between 2010 and 2015 from the SEER database. We used propensity score matching (PSM) to reduce confounding factors between groups and matched each PC patient witha history of thyroid cancerwith 10 PC patients without a history of thyroid cancer. Finally, we selected 103 PC patients with prior thyroid cancer and 1030 PC patients without prior thyroid cancer. Then, we analyzed the factors influencing the overall survival (OS) and the cancer-specific survival (CSS) of PC patients. The median overall survival of PC patients with and without a history of thyroid cancer was 12 and 9 months, respectively. The history of thyroid cancer in PC patients reduced the PC-specific mortality (p < 0.05). Prior thyroid cancer might increase PC patients’ survival and reduce PC-specific death, especially in male patients. Subject terms: Cancer

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Section: Association Between the History Of Thyroid Cancer And Pc-spe...mentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

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Value of thyroid cancer history in the prognosis of pancreatic cancer: a SEER population-based study

Wang

Chen

et al. 2022

Preprint

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show abstract

“…For example, hypothyroidism is associated with autoimmune pancreatitis, a potential risk factor for PC 8 , 9 . Prior thyroid cancer has been found in many studies as a favorable prognostic factor for second primary tumors 10 , 11 . Thyroid cancer is also beneficial for the survival of subsequent liver cancer 10 and breast cancer 11 .…”

Section: Introductionmentioning

confidence: 99%

“…Prior thyroid cancer has been found in many studies as a favorable prognostic factor for second primary tumors 10 , 11 . Thyroid cancer is also beneficial for the survival of subsequent liver cancer 10 and breast cancer 11 . Nevertheless, research about the association between prior thyroid cancer and PC is rare, and further studies are required on these two cancers with very different prognoses.…”

Section: Introductionmentioning

confidence: 99%

Value of thyroid cancer history in the prognosis of pancreatic cancer: a SEER population-based study

Wang

Chen

et al. 2023

Sci Rep

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Thyroid cancer patients have a good prognosis, and their long survival increases the likelihood of developing a second primary tumor. Meanwhile, pancreatic cancer (PC) has a poor prognosis and therapeutic efficacy. However, the association between prior thyroid cancer and the subsequent PC prognosis is unknown. Herein, we selected pathologically diagnosed PC patients older than 17 between 2010 and 2015 from the SEER database. We used propensity score matching (PSM) to reduce confounding factors between groups and matched each PC patient with a history of thyroid cancer with 10 PC patients without a history of thyroid cancer. Finally, we selected 103 PC patients with prior thyroid cancer and 1030 PC patients without prior thyroid cancer. Then, we analyzed the factors influencing the overall survival (OS) and the cancer-specific survival (CSS) of PC patients. The median overall survival of PC patients with and without a history of thyroid cancer was 12 and 9 months, respectively. The history of thyroid cancer in PC patients reduced the PC-specific mortality (p < 0.05). Prior thyroid cancer might be a favorable prognostic factor for PC-specific mortality in PC patients.

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The effect of thyroid cancer on the survival of patients with digestive system tumors using SEER database

Zuo,

Zhou,

Zheng

et al. 2024

Sci Rep

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The number of cancer survivors worldwide is increasing every year, making secondary primary cancers (SPC) is a growing health threat. Studies have been conducted to investigate the risk of occurrence between digestive system tumors (DST) and thyroid cancer (TC). However, existing studies have tended to focus more on the risk of developing SPC and less on the impact of SPC on the survival of cancer survivors. In this study, using the Surveillance, Epidemiology, and End Results database, we aimed to explore the impact of TC on the survival of patients with DST by data between 2000 and 2018. The study employed the standardized incidence ratio to assess the relative risk of SPC, propensity score matching was conducted to mitigate confounding effects, Kaplan-Meier, Cox proportional risk model and competitive risk model were used to analyze the factors affecting the overall survival and cancer-specific survival. We furthermore explored the influence of pathological types and radiotherapy of TC on the survival of DST patients. 518,901 patients with DST only, 801 patients with TC occurring earlier than DST (TC-1st), and 744 patients with DST occurring earlier than TC (DST-1st) were included. The total incidence rate of small intestine cancer after TC was higher than that of the general population, and the incidence of TC after DST was higher than in the general population. DST patients with a history of TC had better overall survival and lower cancer-specific mortality and this difference was particularly significant in patients with DST-1st. In addition, radiotherapy for TC had no effect on cancer-specific mortality in patients with DST.

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Effect of prior thyroid cancer on survival of primary liver cancer: a study based on the SEER database

Cited by 4 publications

References 34 publications

Value of thyroid cancer history in the prognosis of pancreatic cancer: a SEER population-based study

Value of thyroid cancer history in the prognosis of pancreatic cancer: a SEER population-based study

Value of thyroid cancer history in the prognosis of pancreatic cancer: a SEER population-based study

The effect of thyroid cancer on the survival of patients with digestive system tumors using SEER database

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