Effect of proactive infection control measures on benchmarked rate of hospital outbreaks: An analysis of public hospitals in Hong Kong over 5 years

Cheng, Vincent Chi-Chung; Tai, Josepha W.M.; Wong, Lisa M.W.; Ching, Radley H.C.; Ng, Modissa M.L.; Ho, Sara K.Y.; Lee, Doris W.Y.; Li, W.S.; Lee, W.M.; Sridhar, Siddharth; Wong, Sally Cheuk-Ying; Ho, Pak‐Leung; Yuen, Kwok‐Yung

doi:10.1016/j.ajic.2015.04.203

Cited by 20 publications

(14 citation statements)

References 24 publications

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“…23 Other factors included a shortage of well-designed infection control programs that targeted health care workers during their clinical practices. 24 Although nurses in this study showed acceptable knowledge about isolation precaution, their compliance was poor. The results show that few nurses reported that they followed standard isolation precautions (52.7%).…”

Section: Never and Sometimes Alwaysmentioning

confidence: 73%

Knowledge and practices of isolation precautions among nurses in Jordan

Suliman

Aloush

Aljezawi

et al. 2018

American Journal of Infection Control

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Section: Never and Sometimes Alwaysmentioning

confidence: 73%

Knowledge and practices of isolation precautions among nurses in Jordan

Suliman

Aloush

Aljezawi

et al. 2018

American Journal of Infection Control

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“…Additionally, directly observed hand hygiene before meals and oral medication administration by conscious residents should be promoted to prevent ingestion of MDROs into the gastrointestinal tract. 6,10 We are aware of several limitations in this study. First, we did not screen patients who were demented or mentally incapacitated and had not undergone interval screening.…”

Section: Discussionmentioning

confidence: 98%

Emergence of Carbapenem-Resistant Acinetobacter baumannii in Nursing Homes With High Background Rates of MRSA Colonization

Cheng

Chen

Ng³

et al. 2016

Infect. Control Hosp. Epidemiol.

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Carbapenem-resistant Acinetobacter baumannii (CRAB) with diverse multilocus sequence typing emerged among our nursing home residents (6.5%) with a high background rate of MRSA (32.2%). Rectal swabs yielded a higher rate of CRAB detection than axillary or nasal swabs. Bed-bound status, use of adult diapers, and nasogastric tube were risk factors for CRAB colonization. Infect Control Hosp Epidemiol 2016;37:983-986.

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“…Upon identification of gastrointestinal colonization of CPE, infection control nurses would advise appropriate infection control measures as described previously. 11,[15][16][17] Briefly, patients were placed in single-room isolation with strict contact precautions. Cleaning staff was specifically trained to perform meticulous disinfection of high-touch areas, such as bedrail, bedside table, and locker.…”

Section: Settingmentioning

confidence: 99%

A Novel Risk Factor Associated With Colonization by Carbapenemase-Producing Enterobacteriaceae: Use of Proton Pump Inhibitors in Addition to Antimicrobial Treatment

Cheng

Chen

et al. 2016

Infect. Control Hosp. Epidemiol.

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OBJECTIVETo study the association between gastrointestinal colonization of carbapenemase-producing Enterobacteriaceae (CPE) and proton pump inhibitors (PPIs).METHODSWe analyzed 31,526 patients with prospective collection of fecal specimens for CPE screening: upon admission (targeted screening) and during hospitalization (opportunistic screening, safety net screening, and extensive contact tracing), in our healthcare network with 3,200 beds from July 1, 2011, through December 31, 2015. Specimens were collected at least once weekly during hospitalization for CPE carriers and subjected to broth enrichment culture and multiplex polymerase chain reaction.RESULTSOf 66,672 fecal specimens collected, 345 specimens (0.5%) from 100 patients (0.3%) had CPE. The number and prevalence (per 100,000 patient-days) of CPE increased from 2 (0.3) in 2012 to 63 (8.0) in 2015 (P<.001). Male sex (odds ratio, 1.91 [95% CI, 1.15–3.18], P=.013), presence of wound or drain (3.12 [1.70–5.71], P<.001), and use of cephalosporins (3.06 [1.42–6.59], P=.004), carbapenems (2.21 [1.10–4.48], P=.027), and PPIs (2.84 [1.72–4.71], P<.001) in the preceding 6 months were significant risk factors by multivariable analysis. Of 79 patients with serial fecal specimens, spontaneous clearance of CPE was noted in 57 (72.2%), with a median (range) of 30 (3–411) days. Comparing patients without use of antibiotics and PPIs, consumption of both antibiotics and PPIs after CPE identification was associated with later clearance of CPE (hazard ratio, 0.35 [95% CI, 0.17–0.73], P=.005).CONCLUSIONSConcomitant use of antibiotics and PPIs prolonged duration of gastrointestinal colonization by CPE.Infect Control Hosp Epidemiol 2016;1418–1425

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Effect of proactive infection control measures on benchmarked rate of hospital outbreaks: An analysis of public hospitals in Hong Kong over 5 years

Abstract: The results of this large study on benchmarked rate of hospital outbreaks per patient discharges or patient-days suggests that proactive infection control interventions may minimize the risk of hospital outbreaks.

Cited by 20 publications

References 24 publications

Knowledge and practices of isolation precautions among nurses in Jordan

Knowledge and practices of isolation precautions among nurses in Jordan

Emergence of Carbapenem-Resistant Acinetobacter baumannii in Nursing Homes With High Background Rates of MRSA Colonization

A Novel Risk Factor Associated With Colonization by Carbapenemase-Producing Enterobacteriaceae: Use of Proton Pump Inhibitors in Addition to Antimicrobial Treatment

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