Effect of Probiotic Administration on Acute Inflammatory Pain

Shadnoush, Mahdi; Nazemian, Vida; Manaheji, Homa; Zaringhalam, Jalal

doi:10.17795/mejrh-42022

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…It strengthens natural immunity by stimulation of mucosal and systemic host immunity, which is manifested through activated macrophages, increased levels of immunoglobulins, higher levels of natural killer (NK) cell activities and cytokines in the host body (Ashraf and Shah, 2014). So, curd can be used for the treatment of allergy, urinogenital infections, HIV, cancer, liver disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and pancreatitis (Shadnoush et al, 2013). Therefore, it seems necessary to develop pro-health attitudes and beliefs that encourage consumption of these products within the framework of national nutritional guidelines, which may protect and help and contribute to reducing the incidence of chronic non-communicable diseases in various age groups of the population (Danielewicz et al, 2022).…”

Section: Introdutionmentioning

confidence: 99%

Preparation of Low Fat Lassi by Incorporation of Ginger (Zingiber officinale L.) Juice

Raje-Nimbalkar,

Patil,

Raskar

et al. 2023

IJBSM

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The study was conducted at Dept. of Animal Husbandry and Dairy Science, Dr. BSKKV, Dapoli, Ratnagiri, Maharashtra, India during August 2010–January 2011 to evaluate the suitability of ginger juice as flavoring agent in developing ginger lassi. Lassi is a cultured milk beverage and a popular product in India, In Maharashtra also generally lassi is prepared from buffalo milk curd which gives creamy appearance with pleasant mildly acidic sweet taste and rich aroma. The functionality of Lassi increases with the addition of probiotic microorganisms and incorporation of antioxidant rich fruit juice provides strong antioxidant power endow with value addition to the finished product. Ginger is mostly used to cure nausea, ulcer, stroke, Sore throat, Hypertension, indigestion, and Arthritis. Ginger appears to be promising for safe use in medicine, pharmaceutical and food industries. Ginger is a popular home remedy in India today. Hence forth considering the medicinal properties of ginger and use of skim milk in restricting the caloric intake. The lassi was prepared from buffalo skim milk by using ginger juice at different levels viz. 1.5% (T1), 3.0% (T2), 4.5% (T3) and 6.0% (T4) of the content. This prepared lassi was compared with control lassi (T0) i.e. without addition of ginger juice. Ginger juice could be successfully utilized for preparation of herbal lassi. The most acceptable quality lassi can be prepared by using 3.0% ginger juice and It recorded on an average total solid, fat, protein, ash, and acidity as 18.49, 0.52, 3.43, 0.78, and 0.79% respectively.

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Section: Introdutionmentioning

confidence: 99%

Preparation of Low Fat Lassi by Incorporation of Ginger (Zingiber officinale L.) Juice

Raje-Nimbalkar,

Patil,

Raskar

et al. 2023

IJBSM

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Long term treatment by mesenchymal stem cells conditioned medium modulates cellular, molecular and behavioral aspects of adjuvant-induced arthritis

Nazemian

Manaheji

Sharifi

et al. 2018

Cell Mol Biol (Noisy-le-grand)

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Neuroinflammation plays a crucial role in expression of symptoms of numerous autoimmune and neurodegenerative diseases such as pain during rheumatoid arthritis. Overproduction of pro-inflammatory cytokines and activation of intracellular signaling pathways have been strongly implicated in the generation of pathological pain states, particularly at central nervous system sites and induction of spinal neuroinflammatory symptoms. The wide ranges of research to define new therapeutic approaches, including neuroimmune-modulators like stem cells are in progress. Mesenchymal stem cells conditioned medium (MSC-CM) has anti-inflammatory factors which can regulate the immune responses. The aim of this study was to investigate the effect of administration of MSC-CM on behavioral, cellular and molecular aspects of adjuvant-induced arthritis in male Wistar rats. Complete Freund's adjuvant (CFA)-induced arthritis (AA) was caused by single subcutaneous injection of CFA into the rat's hind paw on day 0. MSC-CM was administered daily (i.p.) and during the 21 days of the study after injection. Hyperalgesia, Edema, Serum TNF-α levels and p38MAPK and NF-κB activities were assessed on days 0,7,14 and 21 of the study. The results of this study indicated the role of MSC-CM in reducing inflammatory symptoms, serum TNF-α levels and activity of intracellular signaling pathway factors during different phases of inflammation caused by CFA. It seems that MSC-CM treatment due to its direct effects on inhibition of intracellular signaling pathways and pro-inflammatory cytokines can alleviate inflammatory symptoms and pain during CFA-induced arthritis.

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Effect of Probiotic Administration on Acute Inflammatory Pain

Cited by 2 publications

References 23 publications

Preparation of Low Fat Lassi by Incorporation of Ginger (Zingiber officinale L.) Juice

Preparation of Low Fat Lassi by Incorporation of Ginger (Zingiber officinale L.) Juice

Long term treatment by mesenchymal stem cells conditioned medium modulates cellular, molecular and behavioral aspects of adjuvant-induced arthritis

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