Effect of probiotic and prebiotic fermented milk on skin and intestinal conditions in healthy young female students

Abstract

Although persistent constipation is considered to be associated with skin problems, the supporting evidence is limited. Hence, this study investigated the effects of probiotic and prebiotic fermented milk on skin and intestinal conditions in an open-label trial. Among the 101 Japanese healthy young female students that participated, the 81 subjects in the intake group consumed a bottle of probiotic and prebiotic fermented milk containing Bifidobacterium breve strain Yakult and galactooligosaccharides daily for 4 weeks after a pre-intake period of 4 weeks, while the 20 subjects in the non-intake group did not consume the test beverage. Defecation patterns, skin conditions including hydration levels in the stratum corneum, and urinary phenol and p-cresol levels were evaluated before (baseline) and after intake. All subjects completed the study. No differences in dietary intake and body mass index were observed between both groups during the trial. In the intake group, hydration levels of the stratum corneum, defecation frequency, and feces quantity significantly increased, and urinary phenol and p-cresol levels significantly decreased after intake compared with the corresponding baseline values. However, they did not significantly change in the non-intake group. A significant difference was observed between the intake group and non-intake group in regard to clearness of the skin as assessed by visual analogue scale. Therefore, consecutive intake of probiotic and prebiotic fermented milk might have beneficial effects on the skin that prevent dryness and beneficial effects on the intestinal conditions that stimulate defecation and decrease phenol production by gut bacteria in healthy young women.

Functional Role of Probiotics and Prebiotics on Skin Health and Disease

“…There is a rather small number of studies on healthy subjects to show a beneficial effect of probiotics on skin health (Figure 1) [18,61,[90][91][92]. In one such study, when the L. lactis strain; H61 was supplemented on middle-aged women, daily for eight weeks, an improvement on skin elasticity and body characteristics were observed (e.g., skin appeared more hydrated and the hair follicles had improved) [92].…”

“…Most common species of probiotics belong in the families of Lactobacillus, Bifidobacterium and Streptococcus [9] with the first two families being mostly used in studies related to human health [10]. As these microorganisms are naturally found in the gut microbiota, most studies are focused on their effects in the context of the natural function in the gut and as preventive or therapeutic agents against disease development [11][12][13][14][15][16][17][18]. To this end, probiotics have been used for the study and treatment of intestinal diseases such as gastroenteritis [19], intestinal hyperpermeability [20], urinary tract infection [21], intestinal dysbiosis [22], irritable bowel syndrome [23], Crohn's disease [24], colon cancer [25,26], ulcerative colitis [27,28] and peptic ulcer [23].…”

New lactic acid bacteria for skin health via oral intake of heat‐killed or live cells

“…Miyazaki, Masuoka, Kano, and Iizuka (2014) suggest that intake of certain probiotics and/or prebiotics (nondigestible food ingredients that stimulate the growth of beneficial bacteria in the colon) improves intestinal microbial balance, and thereby reduces phenol production, which is associated with maintenance of good skin condition. Mori et al (2016) reported that intake of fermented milk containing B. breve strain Yakult plus galactooligosaccharides prevented dryness in human skin via beneficial effects on intestinal conditions that stimulate defecation and decrease phenol production.…”

Микробиота Кожи И Возможности Ее Коррекции Пре- И Пробиотиками При Лечении Хронических Дерматозов

“…Разработаны пробиотики на основе монокультур, поликомпонентные препараты, пробиотики на основе нетипичных для нормальной микрофлоры микроорганиз-мов, симбиотики (комбинации про-и пребио-тиков), препараты на основе рекомбинантных генно-инженерных штаммов, мультибиотики. Доказано, что пробиотики обладают способно-стью уменьшать популяцию вредных кишечных бактерий и улучшать состояние кожи [80][81][82][83][84][85][86]. Недавние исследования показали, что проби-отики могут улучшить течение АД, заживление ран и шрамов и способствуют омоложению кожи.…”

“…Все больше данных свидетельствуют о том, что потребление потенциально пробиотиче-ских молочнокислых бактерий может улучшить здоровье кожи [8,[90][91][92][93]. Предполагают, что этому способствует ограничение неблагопри-ятной кишечной бактериальной популяции, производящей фенолы, которые могут нару-шать состояние кожи [8,91].…”