Effect of Progressive Addition Lenses on Myopia Progression in Japanese Children: A Prospective, Randomized, Double-Masked, Crossover Trial

Hasebe, Shinji; Ohtsuki, Hiroshi; Nonaka, Takafumi; Nakatsuka, C.; Miyata, Manabu; Hamasaki, Ichiro; Kimura, Shuhei

doi:10.1167/iovs.07-0385

Cited by 125 publications

(118 citation statements)

References 47 publications

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“…The value of using this selection criterion to identify children with high myopic progression is confirmed: the 24-month rate of myopic progression of −1.55 D in the single-vision lens group (control group) is greater than those of previous myopiacontrol studies. [8][9][10][11][12][13] Our study supports the findings of Leung and Brown, 9 who used a similar inclusion criterion; progressive lenses are effective at inhibiting myopic progression for myopic children with high myopic progression.…”

Section: Commentsupporting

confidence: 81%

Randomized Trial of Effect of Bifocal and Prismatic Bifocal Spectacles on Myopic Progression

Cheng¹

2010

Arch Ophthalmol

116

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To determine whether bifocal and prismatic bifocal spectacles could control myopia in children with high rates of myopic progression.Methods: This was a randomized controlled clinical trial. One hundred thirty-five (73 girls and 62 boys) myopic Chinese Canadian children (myopia of Ն1.00 diopters [D]) with myopic progression of at least 0.50 D in the preceding year were randomly assigned to 1 of 3 treatments: (1) single-vision lenses (n = 41), (2) ϩ1.50-D executive bifocals (n = 48), or (3) ϩ1.50-D executive bifocals with a 3-prism diopters base-in prism in the near segment of each lens (n = 46). Main Outcome Measures: Myopic progression measured by an automated refractor under cycloplegia and increase in axial length (secondary) measured by ultrasonography at 6-month intervals for 24 months. Only the data of the right eye were used.Results: Of the 135 children (mean age, 10.29 years [SE, 0.15 years]; mean visual acuity, −3.08 D [SE, 0.10 D]), 131 (97%) completed the trial after 24 months. Myopic progression averaged −1.55 D (SE, 0.12 D) for those who wore single-vision lenses, −0.96 D (SE, 0.09 D) for those who wore bifocals, and −0.70 D (SE, 0.10 D) for those who wore prismatic bifocals. Axial length increased an average of 0.62 mm (SE, 0.04 mm), 0.41 mm (SE, 0.04 mm), and 0.41 mm (SE, 0.05 mm), respectively. The treatment effect of bifocals (0.59 D) and prismatic bifocals (0.85 D) was significant (PϽ.001) and both bifocal groups had less axial elongation (0.21 mm) than the singlevision lens group (P Ͻ.001).Conclusions: Bifocal lenses can moderately slow myopic progression in children with high rates of progression after 24 months.Applications to Clinical Practice: Bifocal spectacles may be considered for slowing myopic progression in children with an annual progression rate of at least 0.50 D.

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Section: Commentsupporting

confidence: 81%

Randomized Trial of Effect of Bifocal and Prismatic Bifocal Spectacles on Myopic Progression

Cheng¹

2010

Arch Ophthalmol

116

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“…Similarly, bifocal spectacles have been reported to prevent progression of mild or moderate myopia. 42,43 These studies showed an overall adjusted 3-year treatment effect of 0.29 D, which is statistically significant (P ¼ 0.004) but not clinically meaningful. A recent meta-analysis highlighted the effect size from various interventions using single vision lenses as a reference (Table 2).…”

Section: Discussionmentioning

confidence: 88%

Genipin-Crosslinked Donor Sclera for Posterior Scleral Contraction/Reinforcement to Fight Progressive Myopia

Xue

Zheng

Tan

et al. 2018

Invest. Ophthalmol. Vis. Sci.

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PURPOSE. Myopia has become a global public health problem, particularly in East Asia where myopic retinopathy has become one of the leading causes of blindness and visual impairment in the elderly population. The purpose of this study was to evaluate the efficacy of posterior scleral contraction/reinforcement (PSCR) surgery on controlling the progressive elongation of axial length of highly myopic eyes in young patients.METHODS. This is a prospective self-controlled interventional case series. Forty young patients (<18-years old) with progressive high myopia received PSCR with a genipin-crosslinked donor scleral strip for one eye and the fellow eye served as concurrent control without surgery. The main outcome measurement was the change of axial length over 2 to 3 years of follow-up. RESULTS.Immediately after the surgery, axial length was shortened and subsequently increased by 0.32 mm over the follow-up period. In contrast, axial length of the fellow eyes increased by 0.82 mm over the same period (P < 0.001, paired t-test). PSCR delayed axial elongation in eyes with or without staphyloma. No significant change of visual acuity, cornea refractive power, or retina thickness was noted between the surgery and fellow eyes. None of the patients lost visual acuity compared with the baseline. The procedure was well tolerated with only temporary corneal refractive axis shifts that recovered by the 6-month postsurgical visit.CONCLUSIONS. PSCR with genipin-crosslinked sclera is safe and effective to restrain eye globe elongation in young patients within a 2-to 3-year follow-up period.

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“…54 Other studies found similar results with a small difference between PAL and conventional lenses. [55][56][57] Similarly, a more recent trial involving high-risk groups that is, children with high accommodative lags and near-point esophoria also failed to produce any significant benefits. 58 A more recent trial involving children with myopia randomised to wear single-vision spectacles or executive bifocals with þ 1.50 D add or þ 1.50 D add with 3D base in prism found that over a period of 24 months, myopia progression was on average À 1.55 D for those wearing single-vision spectacles, À 0.96 D for those with executive bifocals, and À 0.70 D for those with executive bifocals with base in prisms.…”

Section: Undercorrectionmentioning

confidence: 99%

Practical applications to modify and control the development of ametropia

Sankaridurg¹,

Holden²

2013

Eye

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For many individuals, the developmental trend of lessening hyperopia from birth continues past emmetropia towards myopia during childhood. The global pattern for prevalence of refractive errors indicates that the prevalence of hyperopia is low; in contrast, the burden of myopia is on the rise because of rising prevalence and magnitude of myopia. This review highlights the need to lessen the global burden of myopia by intervening with the development and/or slowing the progression of myopia. Further, outcomes from human clinical trials of pharmaceutical, optical, and environmental approaches to control myopia will be summarised. Pharmaceutical treatments are effective in controlling eye growth but are associated with deleterious side effects. Optical strategies that induce myopic defocus at the retina such as peripheral defocus reducing lenses, simultaneous defocus lenses, bifocals, and orthokeratology as well as environmental influences such as increased outdoor activity show promise and provide a substantially risk-free environment in which to control eye growth.

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Effect of Progressive Addition Lenses on Myopia Progression in Japanese Children: A Prospective, Randomized, Double-Masked, Crossover Trial

Cited by 125 publications

References 47 publications

Randomized Trial of Effect of Bifocal and Prismatic Bifocal Spectacles on Myopic Progression

Randomized Trial of Effect of Bifocal and Prismatic Bifocal Spectacles on Myopic Progression

Genipin-Crosslinked Donor Sclera for Posterior Scleral Contraction/Reinforcement to Fight Progressive Myopia

Practical applications to modify and control the development of ametropia

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